KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18B
All Species:
16.06
Human Site:
S354
Identified Species:
29.44
UniProt:
Q86Y91
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y91
NP_001073912
844
92195
S354
R
A
K
E
I
R
L
S
L
K
S
N
V
T
S
Chimpanzee
Pan troglodytes
XP_001146309
824
90098
S331
M
I
A
A
I
S
P
S
S
L
T
Y
E
D
T
Rhesus Macaque
Macaca mulatta
XP_001102269
881
96385
S354
R
A
K
E
I
R
L
S
L
K
S
N
V
T
S
Dog
Lupus familis
XP_548055
762
82876
S282
E
G
A
N
I
N
R
S
L
L
A
L
I
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6PFD6
834
91918
T343
T
Y
E
D
T
Y
N
T
L
K
Y
A
D
R
A
Rat
Rattus norvegicus
Q4KLL9
826
91176
T343
T
Y
E
D
T
Y
N
T
L
K
Y
A
D
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLK6
797
86563
L312
R
D
S
K
L
T
R
L
L
K
D
S
I
G
G
Frog
Xenopus laevis
Q7ZXX2
997
114958
R349
R
A
K
N
I
K
T
R
V
K
R
N
L
L
N
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
T356
R
A
K
E
I
K
S
T
L
R
S
N
V
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523992
814
92332
T333
S
S
L
T
Y
E
D
T
Y
N
T
L
K
Y
A
Honey Bee
Apis mellifera
XP_001119963
717
81330
A237
V
A
G
L
K
I
I
A
I
Q
S
A
E
E
L
Nematode Worm
Caenorhab. elegans
P46873
699
78760
E219
V
Y
V
E
G
M
T
E
T
G
S
I
R
M
G
Sea Urchin
Strong. purpuratus
P46872
699
78679
A219
E
S
S
S
R
S
H
A
I
F
T
I
T
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
88.1
71.8
N.A.
71.8
72.8
N.A.
N.A.
54.1
28.8
37.9
N.A.
32.9
33.7
27.9
26
Protein Similarity:
100
96.5
90.2
78
N.A.
80.3
81
N.A.
N.A.
64.5
46.9
51.9
N.A.
48.2
51.1
43.5
45
P-Site Identity:
100
13.3
100
20
N.A.
13.3
13.3
N.A.
N.A.
20
40
66.6
N.A.
0
13.3
13.3
0
P-Site Similarity:
100
26.6
100
33.3
N.A.
40
40
N.A.
N.A.
46.6
66.6
86.6
N.A.
26.6
40
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
39
16
8
0
0
0
16
0
0
8
24
0
0
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
16
0
0
8
0
0
0
8
0
16
8
0
% D
% Glu:
16
0
16
31
0
8
0
8
0
0
0
0
16
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
8
8
0
8
0
0
0
0
8
0
0
0
8
16
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
47
8
8
0
16
0
0
16
16
0
0
% I
% Lys:
0
0
31
8
8
16
0
0
0
47
0
0
8
0
0
% K
% Leu:
0
0
8
8
8
0
16
8
54
16
0
16
8
16
8
% L
% Met:
8
0
0
0
0
8
0
0
0
0
0
0
0
16
0
% M
% Asn:
0
0
0
16
0
8
16
0
0
8
0
31
0
8
8
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
39
0
0
0
8
16
16
8
0
8
8
0
8
16
0
% R
% Ser:
8
16
16
8
0
16
8
31
8
0
39
8
0
0
24
% S
% Thr:
16
0
0
8
16
8
16
31
8
0
24
0
8
16
8
% T
% Val:
16
0
8
0
0
0
0
0
8
0
0
0
24
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
24
0
0
8
16
0
0
8
0
16
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _