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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF18B All Species: 4.85
Human Site: S404 Identified Species: 8.89
UniProt: Q86Y91 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86Y91 NP_001073912 844 92195 S404 P P Q D L P G S P K S G P P P
Chimpanzee Pan troglodytes XP_001146309 824 90098 L383 L Q A E V A A L R K K L Q V Y
Rhesus Macaque Macaca mulatta XP_001102269 881 96385 S404 P K Q Y L P R S P K S G P P P
Dog Lupus familis XP_548055 762 82876 A328 N C H T V M I A T V S P S S L
Cat Felis silvestris
Mouse Mus musculus Q6PFD6 834 91918 M391 F L R E K L Q M Y E A G A Q A
Rat Rattus norvegicus Q4KLL9 826 91176 Q390 A A L R E K L Q T Y E A G A Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLK6 797 86563 S358 E I K L S L K S N V L S L D C
Frog Xenopus laevis Q7ZXX2 997 114958 S486 E T Y G K D D S E K D S D T G
Zebra Danio Brachydanio rerio NP_956533 895 100965 R449 N E S R L T M R H R E S W H Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523992 814 92332 K379 V A E N E R L K E R N K A L E
Honey Bee Apis mellifera XP_001119963 717 81330 L283 Y I N I T N K L D G Q V R Q V
Nematode Worm Caenorhab. elegans P46873 699 78760 V265 S L S A L G N V I S A L V D G
Sea Urchin Strong. purpuratus P46872 699 78679 K265 G A T G Q R L K E A T K I N L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96 88.1 71.8 N.A. 71.8 72.8 N.A. N.A. 54.1 28.8 37.9 N.A. 32.9 33.7 27.9 26
Protein Similarity: 100 96.5 90.2 78 N.A. 80.3 81 N.A. N.A. 64.5 46.9 51.9 N.A. 48.2 51.1 43.5 45
P-Site Identity: 100 6.6 80 6.6 N.A. 6.6 0 N.A. N.A. 6.6 13.3 6.6 N.A. 0 0 6.6 0
P-Site Similarity: 100 20 80 20 N.A. 33.3 0 N.A. N.A. 13.3 13.3 13.3 N.A. 26.6 0 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 24 8 8 0 8 8 8 0 8 16 8 16 8 8 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 8 0 8 8 0 8 0 8 0 8 16 0 % D
% Glu: 16 8 8 16 16 0 0 0 24 8 16 0 0 0 8 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 16 0 8 8 0 0 8 0 24 8 0 16 % G
% His: 0 0 8 0 0 0 0 0 8 0 0 0 0 8 0 % H
% Ile: 0 16 0 8 0 0 8 0 8 0 0 0 8 0 0 % I
% Lys: 0 8 8 0 16 8 16 16 0 31 8 16 0 0 0 % K
% Leu: 8 16 8 8 31 16 24 16 0 0 8 16 8 8 16 % L
% Met: 0 0 0 0 0 8 8 8 0 0 0 0 0 0 0 % M
% Asn: 16 0 8 8 0 8 8 0 8 0 8 0 0 8 0 % N
% Pro: 16 8 0 0 0 16 0 0 16 0 0 8 16 16 16 % P
% Gln: 0 8 16 0 8 0 8 8 0 0 8 0 8 16 16 % Q
% Arg: 0 0 8 16 0 16 8 8 8 16 0 0 8 0 0 % R
% Ser: 8 0 16 0 8 0 0 31 0 8 24 24 8 8 0 % S
% Thr: 0 8 8 8 8 8 0 0 16 0 8 0 0 8 0 % T
% Val: 8 0 0 0 16 0 0 8 0 16 0 8 8 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 8 0 8 8 0 0 0 0 8 8 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _