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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18B
All Species:
6.06
Human Site:
S416
Identified Species:
11.11
UniProt:
Q86Y91
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y91
NP_001073912
844
92195
S416
P
P
P
E
H
L
P
S
S
P
L
P
P
H
P
Chimpanzee
Pan troglodytes
XP_001146309
824
90098
Q395
Q
V
Y
E
R
G
G
Q
P
P
P
Q
D
L
P
Rhesus Macaque
Macaca mulatta
XP_001102269
881
96385
S416
P
P
P
Q
H
L
P
S
S
P
L
P
P
H
P
Dog
Lupus familis
XP_548055
762
82876
T340
S
S
L
A
Y
E
D
T
Y
N
T
L
K
Y
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6PFD6
834
91918
C403
A
Q
A
L
Q
Q
Q
C
S
P
Q
P
P
T
L
Rat
Rattus norvegicus
Q4KLL9
826
91176
R402
G
A
Q
A
L
Q
Q
R
S
P
Q
P
P
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLK6
797
86563
Y370
L
D
C
H
I
S
K
Y
A
T
I
C
E
Q
L
Frog
Xenopus laevis
Q7ZXX2
997
114958
D498
D
T
G
D
D
Q
S
D
F
I
E
P
P
E
V
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
F461
W
H
Q
Q
S
L
I
F
F
P
D
N
K
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523992
814
92332
Q391
A
L
E
A
K
A
T
Q
L
E
R
A
G
N
S
Honey Bee
Apis mellifera
XP_001119963
717
81330
I295
R
Q
V
K
L
S
M
I
D
L
A
G
S
E
R
Nematode Worm
Caenorhab. elegans
P46873
699
78760
I277
V
D
G
K
S
K
H
I
P
Y
R
D
S
K
L
Sea Urchin
Strong. purpuratus
P46872
699
78679
L277
I
N
L
S
L
S
T
L
G
N
V
I
S
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
88.1
71.8
N.A.
71.8
72.8
N.A.
N.A.
54.1
28.8
37.9
N.A.
32.9
33.7
27.9
26
Protein Similarity:
100
96.5
90.2
78
N.A.
80.3
81
N.A.
N.A.
64.5
46.9
51.9
N.A.
48.2
51.1
43.5
45
P-Site Identity:
100
20
93.3
0
N.A.
26.6
26.6
N.A.
N.A.
0
13.3
13.3
N.A.
0
0
0
0
P-Site Similarity:
100
20
100
20
N.A.
26.6
26.6
N.A.
N.A.
13.3
20
20
N.A.
6.6
6.6
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
8
24
0
8
0
0
8
0
8
8
0
8
8
% A
% Cys:
0
0
8
0
0
0
0
8
0
0
0
8
0
0
0
% C
% Asp:
8
16
0
8
8
0
8
8
8
0
8
8
8
0
0
% D
% Glu:
0
0
8
16
0
8
0
0
0
8
8
0
8
16
8
% E
% Phe:
0
0
0
0
0
0
0
8
16
0
0
0
0
0
0
% F
% Gly:
8
0
16
0
0
8
8
0
8
0
0
8
8
0
0
% G
% His:
0
8
0
8
16
0
8
0
0
0
0
0
0
16
0
% H
% Ile:
8
0
0
0
8
0
8
16
0
8
8
8
0
0
0
% I
% Lys:
0
0
0
16
8
8
8
0
0
0
0
0
16
16
0
% K
% Leu:
8
8
16
8
24
24
0
8
8
8
16
8
0
8
39
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
16
0
8
0
8
0
% N
% Pro:
16
16
16
0
0
0
16
0
16
47
8
39
39
0
24
% P
% Gln:
8
16
16
16
8
24
16
16
0
0
16
8
0
8
0
% Q
% Arg:
8
0
0
0
8
0
0
8
0
0
16
0
0
0
8
% R
% Ser:
8
8
0
8
16
24
8
16
31
0
0
0
24
8
8
% S
% Thr:
0
8
0
0
0
0
16
8
0
8
8
0
0
8
0
% T
% Val:
8
8
8
0
0
0
0
0
0
0
8
0
0
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
8
8
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _