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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18B
All Species:
7.27
Human Site:
S464
Identified Species:
13.33
UniProt:
Q86Y91
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y91
NP_001073912
844
92195
S464
N
S
S
D
Q
E
Q
S
P
E
D
E
D
E
G
Chimpanzee
Pan troglodytes
XP_001146309
824
90098
S443
P
R
A
L
Q
E
E
S
L
G
T
E
A
Q
V
Rhesus Macaque
Macaca mulatta
XP_001102269
881
96385
S464
N
S
S
D
Q
E
Q
S
P
K
D
Q
G
E
G
Dog
Lupus familis
XP_548055
762
82876
R388
Q
A
E
V
A
T
L
R
E
K
L
Q
V
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6PFD6
834
91918
Q451
E
S
L
G
S
D
A
Q
G
Q
E
I
V
E
E
Rat
Rattus norvegicus
Q4KLL9
826
91176
Q450
E
S
L
G
T
D
S
Q
G
Q
G
T
V
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLK6
797
86563
S418
M
E
E
A
V
P
E
S
C
S
A
P
N
V
C
Frog
Xenopus laevis
Q7ZXX2
997
114958
A546
H
A
R
R
L
E
E
A
L
P
K
R
I
S
S
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
I509
N
E
G
W
L
H
R
I
E
N
E
M
K
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523992
814
92332
R439
K
I
K
N
I
N
Y
R
Q
T
L
K
K
E
L
Honey Bee
Apis mellifera
XP_001119963
717
81330
R343
G
A
K
H
I
T
Y
R
D
S
K
L
T
R
L
Nematode Worm
Caenorhab. elegans
P46873
699
78760
K325
L
R
Y
A
N
R
A
K
N
I
K
N
K
P
T
Sea Urchin
Strong. purpuratus
P46872
699
78679
N325
N
I
G
P
A
E
Y
N
Y
D
E
T
I
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
88.1
71.8
N.A.
71.8
72.8
N.A.
N.A.
54.1
28.8
37.9
N.A.
32.9
33.7
27.9
26
Protein Similarity:
100
96.5
90.2
78
N.A.
80.3
81
N.A.
N.A.
64.5
46.9
51.9
N.A.
48.2
51.1
43.5
45
P-Site Identity:
100
26.6
80
0
N.A.
13.3
13.3
N.A.
N.A.
6.6
6.6
6.6
N.A.
6.6
0
0
13.3
P-Site Similarity:
100
46.6
93.3
20
N.A.
33.3
26.6
N.A.
N.A.
20
33.3
20
N.A.
20
6.6
0
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
8
16
16
0
16
8
0
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% C
% Asp:
0
0
0
16
0
16
0
0
8
8
16
0
8
0
0
% D
% Glu:
16
16
16
0
0
39
24
0
16
8
24
16
0
39
24
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
16
16
0
0
0
0
16
8
8
0
8
0
16
% G
% His:
8
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
16
0
0
8
0
8
0
8
16
0
0
% I
% Lys:
8
0
16
0
0
0
0
8
0
16
24
8
24
0
0
% K
% Leu:
8
0
16
8
16
0
8
0
16
0
16
8
0
8
24
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
31
0
0
8
8
8
0
8
8
8
0
8
8
0
0
% N
% Pro:
8
0
0
8
0
8
0
0
16
8
0
8
0
8
0
% P
% Gln:
8
0
0
0
24
0
16
16
8
16
0
16
0
8
0
% Q
% Arg:
0
16
8
8
0
8
8
24
0
0
0
8
0
8
0
% R
% Ser:
0
31
16
0
8
0
8
31
0
16
0
0
0
16
8
% S
% Thr:
0
0
0
0
8
16
0
0
0
8
8
16
8
0
16
% T
% Val:
0
0
0
8
8
0
0
0
0
0
0
0
24
8
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
24
0
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _