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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF18B All Species: 6.67
Human Site: S507 Identified Species: 12.22
UniProt: Q86Y91 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86Y91 NP_001073912 844 92195 S507 K P V V G H F S A R E L D G D
Chimpanzee Pan troglodytes XP_001146309 824 90098 T486 Q M P E Q N P T H A L P E S P
Rhesus Macaque Macaca mulatta XP_001102269 881 96385 S507 N P V V G H L S A Q E L E R D
Dog Lupus familis XP_548055 762 82876 S431 C L A Q R Q Y S L L Q A A N L
Cat Felis silvestris
Mouse Mus musculus Q6PFD6 834 91918 G494 P S V Q A K P G T G Q H S P Q
Rat Rattus norvegicus Q4KLL9 826 91176 G493 P T V Q A K Q G M N Q H S L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLK6 797 86563 T461 P P S S P S P T Q Q T D L Q L
Frog Xenopus laevis Q7ZXX2 997 114958 Q589 L K D N M I R Q K D Y M V Q R
Zebra Danio Brachydanio rerio NP_956533 895 100965 L552 H M E H M S H L I S V Q D Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523992 814 92332 K482 T S Q M E K Y K E E L P S W L
Honey Bee Apis mellifera XP_001119963 717 81330 R386 N T L R Y A N R A K K I K S H
Nematode Worm Caenorhab. elegans P46873 699 78760 Q368 V G V G A P A Q D A F S I E E
Sea Urchin Strong. purpuratus P46872 699 78679 K368 Q K E I E E L K K Q I S E S G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96 88.1 71.8 N.A. 71.8 72.8 N.A. N.A. 54.1 28.8 37.9 N.A. 32.9 33.7 27.9 26
Protein Similarity: 100 96.5 90.2 78 N.A. 80.3 81 N.A. N.A. 64.5 46.9 51.9 N.A. 48.2 51.1 43.5 45
P-Site Identity: 100 0 66.6 6.6 N.A. 6.6 6.6 N.A. N.A. 6.6 0 6.6 N.A. 0 6.6 6.6 0
P-Site Similarity: 100 26.6 80 20 N.A. 13.3 13.3 N.A. N.A. 20 6.6 13.3 N.A. 13.3 33.3 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 24 8 8 0 24 16 0 8 8 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 8 8 0 8 16 0 16 % D
% Glu: 0 0 16 8 16 8 0 0 8 8 16 0 24 8 16 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % F
% Gly: 0 8 0 8 16 0 0 16 0 8 0 0 0 8 8 % G
% His: 8 0 0 8 0 16 8 0 8 0 0 16 0 0 8 % H
% Ile: 0 0 0 8 0 8 0 0 8 0 8 8 8 0 0 % I
% Lys: 8 16 0 0 0 24 0 16 16 8 8 0 8 0 0 % K
% Leu: 8 8 8 0 0 0 16 8 8 8 16 16 8 8 24 % L
% Met: 0 16 0 8 16 0 0 0 8 0 0 8 0 0 0 % M
% Asn: 16 0 0 8 0 8 8 0 0 8 0 0 0 8 0 % N
% Pro: 24 24 8 0 8 8 24 0 0 0 0 16 0 8 8 % P
% Gln: 16 0 8 24 8 8 8 16 8 24 24 8 0 24 16 % Q
% Arg: 0 0 0 8 8 0 8 8 0 8 0 0 0 8 8 % R
% Ser: 0 16 8 8 0 16 0 24 0 8 0 16 24 24 0 % S
% Thr: 8 16 0 0 0 0 0 16 8 0 8 0 0 0 0 % T
% Val: 8 0 39 16 0 0 0 0 0 0 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 8 0 16 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _