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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18B
All Species:
6.67
Human Site:
S516
Identified Species:
12.22
UniProt:
Q86Y91
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y91
NP_001073912
844
92195
S516
R
E
L
D
G
D
R
S
K
Q
L
A
L
K
V
Chimpanzee
Pan troglodytes
XP_001146309
824
90098
L495
A
L
P
E
S
P
G
L
T
L
Q
P
K
P
V
Rhesus Macaque
Macaca mulatta
XP_001102269
881
96385
S516
Q
E
L
E
R
D
R
S
K
Q
L
A
L
K
V
Dog
Lupus familis
XP_548055
762
82876
T440
L
Q
A
A
N
L
L
T
P
D
M
I
T
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q6PFD6
834
91918
Q503
G
Q
H
S
P
Q
K
Q
D
A
D
H
S
K
Q
Rat
Rattus norvegicus
Q4KLL9
826
91176
L502
N
Q
H
S
L
Q
R
L
D
A
E
H
S
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLK6
797
86563
M470
Q
T
D
L
Q
L
G
M
K
K
P
N
R
L
P
Frog
Xenopus laevis
Q7ZXX2
997
114958
E598
D
Y
M
V
Q
R
F
E
Q
H
R
S
L
C
D
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
T561
S
V
Q
D
Q
E
N
T
H
T
H
K
L
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523992
814
92332
K491
E
L
P
S
W
L
S
K
M
E
I
A
Y
Q
D
Honey Bee
Apis mellifera
XP_001119963
717
81330
K395
K
K
I
K
S
H
I
K
K
N
I
I
S
C
E
Nematode Worm
Caenorhab. elegans
P46873
699
78760
R377
A
F
S
I
E
E
E
R
K
K
L
R
E
E
F
Sea Urchin
Strong. purpuratus
P46872
699
78679
G377
Q
I
S
E
S
G
E
G
L
D
D
D
E
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
88.1
71.8
N.A.
71.8
72.8
N.A.
N.A.
54.1
28.8
37.9
N.A.
32.9
33.7
27.9
26
Protein Similarity:
100
96.5
90.2
78
N.A.
80.3
81
N.A.
N.A.
64.5
46.9
51.9
N.A.
48.2
51.1
43.5
45
P-Site Identity:
100
6.6
80
0
N.A.
6.6
13.3
N.A.
N.A.
6.6
6.6
13.3
N.A.
6.6
6.6
13.3
0
P-Site Similarity:
100
13.3
93.3
26.6
N.A.
20
20
N.A.
N.A.
20
26.6
26.6
N.A.
26.6
33.3
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
8
8
0
0
0
0
0
16
0
24
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% C
% Asp:
8
0
8
16
0
16
0
0
16
16
16
8
0
0
16
% D
% Glu:
8
16
0
24
8
16
16
8
0
8
8
0
16
24
8
% E
% Phe:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
16
% F
% Gly:
8
0
0
0
8
8
16
8
0
0
0
0
0
0
0
% G
% His:
0
0
16
0
0
8
0
0
8
8
8
16
0
0
0
% H
% Ile:
0
8
8
8
0
0
8
0
0
0
16
16
0
0
0
% I
% Lys:
8
8
0
8
0
0
8
16
39
16
0
8
8
31
0
% K
% Leu:
8
16
16
8
8
24
8
16
8
8
24
0
31
8
0
% L
% Met:
0
0
8
0
0
0
0
8
8
0
8
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
8
0
0
8
0
8
0
0
8
% N
% Pro:
0
0
16
0
8
8
0
0
8
0
8
8
0
8
8
% P
% Gln:
24
24
8
0
24
16
0
8
8
16
8
0
0
8
16
% Q
% Arg:
8
0
0
0
8
8
24
8
0
0
8
8
8
0
0
% R
% Ser:
8
0
16
24
24
0
8
16
0
0
0
8
24
0
8
% S
% Thr:
0
8
0
0
0
0
0
16
8
8
0
0
8
0
0
% T
% Val:
0
8
0
8
0
0
0
0
0
0
0
0
0
8
24
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _