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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18B
All Species:
3.94
Human Site:
S570
Identified Species:
7.22
UniProt:
Q86Y91
Number Species:
12
Phosphosite Substitution
Charge Score:
0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y91
NP_001073912
844
92195
S570
G
A
E
A
L
R
T
S
G
L
A
R
G
A
P
Chimpanzee
Pan troglodytes
XP_001146309
824
90098
E549
P
D
M
I
T
E
F
E
T
L
Q
Q
L
V
Q
Rhesus Macaque
Macaca mulatta
XP_001102269
881
96385
S570
G
A
E
A
S
S
T
S
G
L
A
R
G
A
P
Dog
Lupus familis
XP_548055
762
82876
G490
S
D
S
P
G
Y
S
G
P
V
T
R
T
M
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6PFD6
834
91918
D553
L
V
L
E
E
S
V
D
H
R
A
E
S
P
R
Rat
Rattus norvegicus
Q4KLL9
826
91176
E552
L
V
L
E
E
S
M
E
H
G
A
E
S
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLK6
797
86563
Q521
V
S
E
F
E
E
L
Q
L
L
V
Q
K
E
A
Frog
Xenopus laevis
Q7ZXX2
997
114958
C656
A
L
K
D
S
Q
S
C
L
P
K
I
P
N
L
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
D620
K
A
E
D
K
R
D
D
S
G
I
G
S
T
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523992
814
92332
I541
F
N
N
H
V
N
A
I
N
Q
E
L
V
E
N
Honey Bee
Apis mellifera
XP_001119963
717
81330
V445
T
D
C
K
N
D
N
V
N
K
E
I
D
K
N
Nematode Worm
Caenorhab. elegans
P46873
699
78760
N427
N
A
N
L
D
N
L
N
P
E
E
A
A
K
K
Sea Urchin
Strong. purpuratus
P46872
699
78679
E427
M
Q
K
K
I
D
E
E
K
K
A
L
E
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
88.1
71.8
N.A.
71.8
72.8
N.A.
N.A.
54.1
28.8
37.9
N.A.
32.9
33.7
27.9
26
Protein Similarity:
100
96.5
90.2
78
N.A.
80.3
81
N.A.
N.A.
64.5
46.9
51.9
N.A.
48.2
51.1
43.5
45
P-Site Identity:
100
6.6
86.6
6.6
N.A.
6.6
6.6
N.A.
N.A.
13.3
0
20
N.A.
0
0
6.6
6.6
P-Site Similarity:
100
13.3
86.6
20
N.A.
6.6
6.6
N.A.
N.A.
26.6
20
20
N.A.
6.6
0
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
31
0
16
0
0
8
0
0
0
39
8
8
16
16
% A
% Cys:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
24
0
16
8
16
8
16
0
0
0
0
8
0
0
% D
% Glu:
0
0
31
16
24
16
8
24
0
8
24
16
8
24
0
% E
% Phe:
8
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
16
0
0
0
8
0
0
8
16
16
0
8
16
0
0
% G
% His:
0
0
0
8
0
0
0
0
16
0
0
0
0
0
8
% H
% Ile:
0
0
0
8
8
0
0
8
0
0
8
16
0
0
0
% I
% Lys:
8
0
16
16
8
0
0
0
8
16
8
0
8
16
16
% K
% Leu:
16
8
16
8
8
0
16
0
16
31
0
16
8
0
8
% L
% Met:
8
0
8
0
0
0
8
0
0
0
0
0
0
8
0
% M
% Asn:
8
8
16
0
8
16
8
8
16
0
0
0
0
8
16
% N
% Pro:
8
0
0
8
0
0
0
0
16
8
0
0
8
16
16
% P
% Gln:
0
8
0
0
0
8
0
8
0
8
8
16
0
0
8
% Q
% Arg:
0
0
0
0
0
16
0
0
0
8
0
24
0
0
16
% R
% Ser:
8
8
8
0
16
24
16
16
8
0
0
0
24
0
0
% S
% Thr:
8
0
0
0
8
0
16
0
8
0
8
0
8
8
0
% T
% Val:
8
16
0
0
8
0
8
8
0
8
8
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _