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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18B
All Species:
2.12
Human Site:
S591
Identified Species:
3.89
UniProt:
Q86Y91
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y91
NP_001073912
844
92195
S591
S
E
S
I
P
V
P
S
P
L
C
P
E
P
P
Chimpanzee
Pan troglodytes
XP_001146309
824
90098
S570
G
A
E
A
L
R
T
S
G
L
A
R
G
A
P
Rhesus Macaque
Macaca mulatta
XP_001102269
881
96385
Y591
S
E
S
K
P
P
G
Y
T
G
P
V
T
R
T
Dog
Lupus familis
XP_548055
762
82876
P511
M
H
T
L
G
V
L
P
G
S
D
C
T
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6PFD6
834
91918
L574
G
D
P
L
A
Q
A
L
C
S
E
S
K
S
S
Rat
Rattus norvegicus
Q4KLL9
826
91176
L573
G
I
P
L
A
Q
E
L
C
S
E
S
K
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLK6
797
86563
P542
T
D
T
S
G
A
P
P
A
L
R
T
Q
R
G
Frog
Xenopus laevis
Q7ZXX2
997
114958
E677
Q
E
P
D
S
D
Q
E
S
V
R
T
F
G
S
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
Q641
F
S
H
L
V
S
H
Q
S
T
P
C
S
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523992
814
92332
V562
S
F
R
T
A
C
E
V
L
N
Q
T
Y
D
R
Honey Bee
Apis mellifera
XP_001119963
717
81330
K466
E
L
I
E
L
L
Q
K
K
K
V
L
N
E
K
Nematode Worm
Caenorhab. elegans
P46873
699
78760
A448
Q
F
I
G
G
E
E
A
G
N
T
Q
L
K
Q
Sea Urchin
Strong. purpuratus
P46872
699
78679
E448
D
R
N
T
V
H
R
E
L
Q
R
R
E
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
88.1
71.8
N.A.
71.8
72.8
N.A.
N.A.
54.1
28.8
37.9
N.A.
32.9
33.7
27.9
26
Protein Similarity:
100
96.5
90.2
78
N.A.
80.3
81
N.A.
N.A.
64.5
46.9
51.9
N.A.
48.2
51.1
43.5
45
P-Site Identity:
100
20
26.6
13.3
N.A.
0
0
N.A.
N.A.
13.3
6.6
0
N.A.
6.6
0
0
6.6
P-Site Similarity:
100
20
26.6
26.6
N.A.
20
13.3
N.A.
N.A.
40
13.3
6.6
N.A.
6.6
6.6
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
24
8
8
8
8
0
8
0
0
8
8
% A
% Cys:
0
0
0
0
0
8
0
0
16
0
8
16
0
0
0
% C
% Asp:
8
16
0
8
0
8
0
0
0
0
8
0
0
8
0
% D
% Glu:
8
24
8
8
0
8
24
16
0
0
16
0
16
8
16
% E
% Phe:
8
16
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
24
0
0
8
24
0
8
0
24
8
0
0
8
8
8
% G
% His:
0
8
8
0
0
8
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
16
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
8
8
8
0
0
16
8
8
% K
% Leu:
0
8
0
31
16
8
8
16
16
24
0
8
8
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
16
0
0
8
0
0
% N
% Pro:
0
0
24
0
16
8
16
16
8
0
16
8
0
16
16
% P
% Gln:
16
0
0
0
0
16
16
8
0
8
8
8
8
0
8
% Q
% Arg:
0
8
8
0
0
8
8
0
0
0
24
16
0
16
8
% R
% Ser:
24
8
16
8
8
8
0
16
16
24
0
16
8
31
24
% S
% Thr:
8
0
16
16
0
0
8
0
8
8
8
24
16
0
8
% T
% Val:
0
0
0
0
16
16
0
8
0
8
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _