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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18B
All Species:
1.52
Human Site:
S685
Identified Species:
2.78
UniProt:
Q86Y91
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y91
NP_001073912
844
92195
S685
T
Q
P
S
Q
G
P
S
T
P
K
G
E
R
A
Chimpanzee
Pan troglodytes
XP_001146309
824
90098
G664
F
L
P
C
L
R
R
G
S
L
P
D
T
Q
P
Rhesus Macaque
Macaca mulatta
XP_001102269
881
96385
S685
T
P
K
G
E
R
A
S
S
P
C
H
S
P
H
Dog
Lupus familis
XP_548055
762
82876
Q605
P
L
G
P
S
A
V
Q
N
C
S
T
P
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6PFD6
834
91918
R668
A
Q
P
C
S
E
P
R
T
P
K
R
E
R
A
Rat
Rattus norvegicus
Q4KLL9
826
91176
R667
I
Q
P
S
S
E
P
R
T
P
K
G
E
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLK6
797
86563
L636
R
S
P
H
T
P
C
L
K
E
P
Q
S
P
P
Frog
Xenopus laevis
Q7ZXX2
997
114958
I771
T
H
R
E
K
K
E
I
T
T
S
I
Q
S
I
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
F735
Q
P
H
T
S
S
I
F
D
P
N
S
T
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523992
814
92332
Q656
S
M
E
D
F
D
S
Q
D
T
E
S
D
S
E
Honey Bee
Apis mellifera
XP_001119963
717
81330
V560
I
Q
K
L
D
A
E
V
K
L
K
K
S
R
L
Nematode Worm
Caenorhab. elegans
P46873
699
78760
L542
K
Q
D
Q
Q
L
K
L
L
M
Q
I
M
D
K
Sea Urchin
Strong. purpuratus
P46872
699
78679
K542
D
E
A
H
G
K
T
K
K
L
K
K
V
W
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
88.1
71.8
N.A.
71.8
72.8
N.A.
N.A.
54.1
28.8
37.9
N.A.
32.9
33.7
27.9
26
Protein Similarity:
100
96.5
90.2
78
N.A.
80.3
81
N.A.
N.A.
64.5
46.9
51.9
N.A.
48.2
51.1
43.5
45
P-Site Identity:
100
6.6
20
6.6
N.A.
60
73.3
N.A.
N.A.
6.6
13.3
6.6
N.A.
0
20
13.3
6.6
P-Site Similarity:
100
20
33.3
6.6
N.A.
60
73.3
N.A.
N.A.
6.6
26.6
13.3
N.A.
20
20
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
16
8
0
0
0
0
0
0
0
31
% A
% Cys:
0
0
0
16
0
0
8
0
0
8
8
0
0
0
0
% C
% Asp:
8
0
8
8
8
8
0
0
16
0
0
8
8
8
8
% D
% Glu:
0
8
8
8
8
16
16
0
0
8
8
0
24
0
8
% E
% Phe:
8
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
8
8
0
8
0
0
0
16
0
0
0
% G
% His:
0
8
8
16
0
0
0
0
0
0
0
8
0
0
8
% H
% Ile:
16
0
0
0
0
0
8
8
0
0
0
16
0
8
8
% I
% Lys:
8
0
16
0
8
16
8
8
24
0
39
16
0
0
8
% K
% Leu:
0
16
0
8
8
8
0
16
8
24
0
0
0
8
8
% L
% Met:
0
8
0
0
0
0
0
0
0
8
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% N
% Pro:
8
16
39
8
0
8
24
0
0
39
16
0
8
16
16
% P
% Gln:
8
39
0
8
16
0
0
16
0
0
8
8
8
8
0
% Q
% Arg:
8
0
8
0
0
16
8
16
0
0
0
8
0
31
0
% R
% Ser:
8
8
0
16
31
8
8
16
16
0
16
16
24
16
0
% S
% Thr:
24
0
0
8
8
0
8
0
31
16
0
8
16
0
8
% T
% Val:
0
0
0
0
0
0
8
8
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _