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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18B
All Species:
13.33
Human Site:
T220
Identified Species:
24.44
UniProt:
Q86Y91
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y91
NP_001073912
844
92195
T220
H
P
T
D
A
N
A
T
S
S
R
S
H
A
I
Chimpanzee
Pan troglodytes
XP_001146309
824
90098
R205
Q
L
L
E
I
L
T
R
G
N
R
N
R
T
Q
Rhesus Macaque
Macaca mulatta
XP_001102269
881
96385
T220
H
P
T
D
A
N
A
T
S
S
R
S
H
A
I
Dog
Lupus familis
XP_548055
762
82876
S156
K
R
F
E
V
L
I
S
Y
Q
E
V
Y
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6PFD6
834
91918
R207
Q
L
L
E
M
L
T
R
G
N
C
S
R
T
Q
Rat
Rattus norvegicus
Q4KLL9
826
91176
R207
Q
L
L
E
M
L
T
R
G
N
C
S
R
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLK6
797
86563
V185
E
D
P
E
K
G
V
V
V
Q
G
L
S
F
H
Frog
Xenopus laevis
Q7ZXX2
997
114958
T216
E
P
T
A
A
N
K
T
S
S
R
S
H
A
I
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
T222
H
P
T
D
M
N
A
T
S
S
R
S
H
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523992
814
92332
G207
L
L
R
M
L
M
L
G
N
S
H
R
T
Q
H
Honey Bee
Apis mellifera
XP_001119963
717
81330
K111
D
L
N
K
K
Q
N
K
E
L
Q
F
I
F
D
Nematode Worm
Caenorhab. elegans
P46873
699
78760
K93
Y
G
Q
T
G
S
G
K
T
F
S
M
Q
G
I
Sea Urchin
Strong. purpuratus
P46872
699
78679
I93
I
E
G
Y
N
G
T
I
F
A
Y
G
Q
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
88.1
71.8
N.A.
71.8
72.8
N.A.
N.A.
54.1
28.8
37.9
N.A.
32.9
33.7
27.9
26
Protein Similarity:
100
96.5
90.2
78
N.A.
80.3
81
N.A.
N.A.
64.5
46.9
51.9
N.A.
48.2
51.1
43.5
45
P-Site Identity:
100
6.6
100
0
N.A.
6.6
6.6
N.A.
N.A.
0
80
86.6
N.A.
6.6
0
6.6
0
P-Site Similarity:
100
26.6
100
20
N.A.
20
20
N.A.
N.A.
6.6
80
93.3
N.A.
13.3
6.6
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
24
0
24
0
0
8
0
0
0
31
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% C
% Asp:
8
8
0
24
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
16
8
0
39
0
0
0
0
8
0
8
0
0
0
8
% E
% Phe:
0
0
8
0
0
0
0
0
8
8
0
8
0
16
0
% F
% Gly:
0
8
8
0
8
16
8
8
24
0
8
8
0
8
8
% G
% His:
24
0
0
0
0
0
0
0
0
0
8
0
31
0
16
% H
% Ile:
8
0
0
0
8
0
8
8
0
0
0
0
8
0
31
% I
% Lys:
8
0
0
8
16
0
8
16
0
0
0
0
0
0
0
% K
% Leu:
8
39
24
0
8
31
8
0
0
8
0
8
0
0
0
% L
% Met:
0
0
0
8
24
8
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
8
31
8
0
8
24
0
8
0
8
0
% N
% Pro:
0
31
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
24
0
8
0
0
8
0
0
0
16
8
0
16
8
24
% Q
% Arg:
0
8
8
0
0
0
0
24
0
0
39
8
24
0
0
% R
% Ser:
0
0
0
0
0
8
0
8
31
39
8
47
8
0
0
% S
% Thr:
0
0
31
8
0
0
31
31
8
0
0
0
8
31
0
% T
% Val:
0
0
0
0
8
0
8
8
8
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
0
0
8
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _