KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18B
All Species:
4.55
Human Site:
T486
Identified Species:
8.33
UniProt:
Q86Y91
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y91
NP_001073912
844
92195
T486
Q
M
P
E
Q
N
P
T
H
A
L
P
E
S
P
Chimpanzee
Pan troglodytes
XP_001146309
824
90098
P465
S
S
D
Q
E
Q
S
P
E
D
E
D
E
G
P
Rhesus Macaque
Macaca mulatta
XP_001102269
881
96385
T486
Q
M
P
E
Q
N
P
T
H
A
L
P
E
S
P
Dog
Lupus familis
XP_548055
762
82876
K410
Q
D
L
P
K
S
P
K
S
G
S
S
Q
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6PFD6
834
91918
P473
C
P
Q
D
K
Q
C
P
T
Q
K
P
E
P
N
Rat
Rattus norvegicus
Q4KLL9
826
91176
P472
P
P
Q
D
K
Q
F
P
T
Q
M
P
E
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLK6
797
86563
D440
Q
E
L
G
A
G
Q
D
A
Q
L
G
G
E
E
Frog
Xenopus laevis
Q7ZXX2
997
114958
E568
S
L
L
C
K
V
H
E
L
E
I
E
N
T
E
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
Q531
E
E
L
K
K
E
L
Q
C
H
Q
L
Q
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523992
814
92332
Q461
C
V
D
Q
R
V
C
Q
E
D
F
R
R
F
A
Honey Bee
Apis mellifera
XP_001119963
717
81330
A365
N
C
Q
T
V
M
I
A
N
I
S
P
S
N
F
Nematode Worm
Caenorhab. elegans
P46873
699
78760
E347
A
L
L
R
E
Y
Q
E
E
I
A
R
L
K
S
Sea Urchin
Strong. purpuratus
P46872
699
78679
K347
K
N
I
K
N
K
A
K
I
N
E
D
P
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
88.1
71.8
N.A.
71.8
72.8
N.A.
N.A.
54.1
28.8
37.9
N.A.
32.9
33.7
27.9
26
Protein Similarity:
100
96.5
90.2
78
N.A.
80.3
81
N.A.
N.A.
64.5
46.9
51.9
N.A.
48.2
51.1
43.5
45
P-Site Identity:
100
13.3
100
13.3
N.A.
13.3
13.3
N.A.
N.A.
13.3
0
0
N.A.
0
6.6
0
0
P-Site Similarity:
100
26.6
100
33.3
N.A.
26.6
33.3
N.A.
N.A.
13.3
26.6
26.6
N.A.
20
20
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
8
8
8
16
8
0
0
0
8
% A
% Cys:
16
8
0
8
0
0
16
0
8
0
0
0
0
0
0
% C
% Asp:
0
8
16
16
0
0
0
8
0
16
0
16
0
0
8
% D
% Glu:
8
16
0
16
16
8
0
16
24
8
16
8
39
8
16
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
8
0
0
8
8
% F
% Gly:
0
0
0
8
0
8
0
0
0
8
0
8
8
8
0
% G
% His:
0
0
0
0
0
0
8
0
16
8
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
0
8
16
8
0
0
0
0
% I
% Lys:
8
0
0
16
39
8
0
16
0
0
8
0
0
16
0
% K
% Leu:
0
16
39
0
0
0
8
0
8
0
24
8
8
8
8
% L
% Met:
0
16
0
0
0
8
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
8
0
0
8
16
0
0
8
8
0
0
8
8
16
% N
% Pro:
8
16
16
8
0
0
24
24
0
0
0
39
8
16
24
% P
% Gln:
31
0
24
16
16
24
16
16
0
24
8
0
16
8
8
% Q
% Arg:
0
0
0
8
8
0
0
0
0
0
0
16
8
0
0
% R
% Ser:
16
8
0
0
0
8
8
0
8
0
16
8
8
16
8
% S
% Thr:
0
0
0
8
0
0
0
16
16
0
0
0
0
8
0
% T
% Val:
0
8
0
0
8
16
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _