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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF18B All Species: 14.55
Human Site: Y344 Identified Species: 26.67
UniProt: Q86Y91 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86Y91 NP_001073912 844 92195 Y344 D T Y N T L K Y A D R A K E I
Chimpanzee Pan troglodytes XP_001146309 824 90098 R321 D S L G G N C R T V M I A A I
Rhesus Macaque Macaca mulatta XP_001102269 881 96385 Y344 D T Y N T L K Y A D R A K E I
Dog Lupus familis XP_548055 762 82876 R272 S T H A K G E R L R E G A N I
Cat Felis silvestris
Mouse Mus musculus Q6PFD6 834 91918 S333 M I A A I S P S S L T Y E D T
Rat Rattus norvegicus Q4KLL9 826 91176 S333 M I A A V S P S S L T Y E D T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLK6 797 86563 I302 A K S K K T H I P Y R D S K L
Frog Xenopus laevis Q7ZXX2 997 114958 Y339 E S R N T L T Y A D R A K N I
Zebra Danio Brachydanio rerio NP_956533 895 100965 Y346 D T H N T L K Y A N R A K E I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523992 814 92332 V323 R T L M V A N V S M S S L T Y
Honey Bee Apis mellifera XP_001119963 717 81330 G227 L R D D G R C G I I V A G L K
Nematode Worm Caenorhab. elegans P46873 699 78760 I209 D S S R S H S I F T V Y V E G
Sea Urchin Strong. purpuratus P46872 699 78679 N209 N R S V G A T N M N E S S S R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96 88.1 71.8 N.A. 71.8 72.8 N.A. N.A. 54.1 28.8 37.9 N.A. 32.9 33.7 27.9 26
Protein Similarity: 100 96.5 90.2 78 N.A. 80.3 81 N.A. N.A. 64.5 46.9 51.9 N.A. 48.2 51.1 43.5 45
P-Site Identity: 100 13.3 100 13.3 N.A. 0 0 N.A. N.A. 6.6 66.6 86.6 N.A. 6.6 6.6 13.3 0
P-Site Similarity: 100 20 100 26.6 N.A. 20 20 N.A. N.A. 20 80 100 N.A. 20 13.3 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 16 24 0 16 0 0 31 0 0 39 16 8 0 % A
% Cys: 0 0 0 0 0 0 16 0 0 0 0 0 0 0 0 % C
% Asp: 39 0 8 8 0 0 0 0 0 24 0 8 0 16 0 % D
% Glu: 8 0 0 0 0 0 8 0 0 0 16 0 16 31 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 24 8 0 8 0 0 0 8 8 0 8 % G
% His: 0 0 16 0 0 8 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 16 0 0 8 0 0 16 8 8 0 8 0 0 47 % I
% Lys: 0 8 0 8 16 0 24 0 0 0 0 0 31 8 8 % K
% Leu: 8 0 16 0 0 31 0 0 8 16 0 0 8 8 8 % L
% Met: 16 0 0 8 0 0 0 0 8 8 8 0 0 0 0 % M
% Asn: 8 0 0 31 0 8 8 8 0 16 0 0 0 16 0 % N
% Pro: 0 0 0 0 0 0 16 0 8 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 16 8 8 0 8 0 16 0 8 39 0 0 0 8 % R
% Ser: 8 24 24 0 8 16 8 16 24 0 8 16 16 8 0 % S
% Thr: 0 39 0 0 31 8 16 0 8 8 16 0 0 8 16 % T
% Val: 0 0 0 8 16 0 0 8 0 8 16 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 16 0 0 0 0 31 0 8 0 24 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _