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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18B
All Species:
5.15
Human Site:
Y600
Identified Species:
9.44
UniProt:
Q86Y91
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y91
NP_001073912
844
92195
Y600
L
C
P
E
P
P
G
Y
T
G
P
V
T
R
T
Chimpanzee
Pan troglodytes
XP_001146309
824
90098
A579
L
A
R
G
A
P
L
A
Q
E
L
C
S
E
S
Rhesus Macaque
Macaca mulatta
XP_001102269
881
96385
V600
G
P
V
T
R
T
M
V
R
R
L
S
G
P
L
Dog
Lupus familis
XP_548055
762
82876
R520
S
D
C
T
P
A
R
R
P
T
E
R
R
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6PFD6
834
91918
Y583
S
E
S
K
S
S
G
Y
C
G
P
V
T
R
T
Rat
Rattus norvegicus
Q4KLL9
826
91176
Y582
S
E
S
K
S
S
R
Y
C
G
P
V
T
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLK6
797
86563
D551
L
R
T
Q
R
G
C
D
A
S
P
S
T
L
S
Frog
Xenopus laevis
Q7ZXX2
997
114958
N686
V
R
T
F
G
S
D
N
R
N
P
I
H
R
D
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
H650
T
P
C
S
S
E
K
H
T
R
R
T
S
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523992
814
92332
E571
N
Q
T
Y
D
R
L
E
D
G
Q
K
L
T
P
Honey Bee
Apis mellifera
XP_001119963
717
81330
L475
K
V
L
N
E
K
I
L
S
L
E
S
A
D
K
Nematode Worm
Caenorhab. elegans
P46873
699
78760
R457
N
T
Q
L
K
Q
K
R
M
K
Q
L
K
E
A
Sea Urchin
Strong. purpuratus
P46872
699
78679
H457
Q
R
R
E
S
E
L
H
K
A
Q
D
D
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
88.1
71.8
N.A.
71.8
72.8
N.A.
N.A.
54.1
28.8
37.9
N.A.
32.9
33.7
27.9
26
Protein Similarity:
100
96.5
90.2
78
N.A.
80.3
81
N.A.
N.A.
64.5
46.9
51.9
N.A.
48.2
51.1
43.5
45
P-Site Identity:
100
13.3
0
13.3
N.A.
53.3
46.6
N.A.
N.A.
20
13.3
6.6
N.A.
6.6
0
0
6.6
P-Site Similarity:
100
26.6
0
13.3
N.A.
60
53.3
N.A.
N.A.
33.3
26.6
26.6
N.A.
6.6
6.6
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
8
0
8
8
8
0
0
8
0
8
% A
% Cys:
0
8
16
0
0
0
8
0
16
0
0
8
0
0
0
% C
% Asp:
0
8
0
0
8
0
8
8
8
0
0
8
8
8
8
% D
% Glu:
0
16
0
16
8
16
0
8
0
8
16
0
0
16
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
8
8
8
16
0
0
31
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
16
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% I
% Lys:
8
0
0
16
8
8
16
0
8
8
0
8
8
0
16
% K
% Leu:
24
0
8
8
0
0
24
8
0
8
16
8
8
8
8
% L
% Met:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% M
% Asn:
16
0
0
8
0
0
0
8
0
8
0
0
0
0
0
% N
% Pro:
0
16
8
0
16
16
0
0
8
0
39
0
0
8
8
% P
% Gln:
8
8
8
8
0
8
0
0
8
0
24
0
0
16
0
% Q
% Arg:
0
24
16
0
16
8
16
16
16
16
8
8
8
39
16
% R
% Ser:
24
0
16
8
31
24
0
0
8
8
0
24
16
0
16
% S
% Thr:
8
8
24
16
0
8
0
0
16
8
0
8
31
8
24
% T
% Val:
8
8
8
0
0
0
0
8
0
0
0
24
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
24
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _