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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECHDC2
All Species:
23.33
Human Site:
Y221
Identified Species:
46.67
UniProt:
Q86YB7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86YB7
NP_060751.2
292
31126
Y221
N
E
E
G
D
A
A
Y
Q
R
A
R
A
L
A
Chimpanzee
Pan troglodytes
XP_001147566
294
31438
Y223
N
E
E
G
D
A
A
Y
Q
R
A
R
A
L
A
Rhesus Macaque
Macaca mulatta
XP_001112245
294
31511
Y223
N
E
E
G
D
A
A
Y
H
R
A
R
A
L
A
Dog
Lupus familis
XP_853370
147
15421
L91
A
A
M
D
G
F
A
L
G
G
G
L
E
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3TLP5
296
31834
Y225
N
E
E
G
N
A
A
Y
H
R
A
L
A
L
A
Rat
Rattus norvegicus
P14604
290
31498
I223
E
T
L
V
E
E
A
I
Q
C
A
E
K
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422480
286
30783
Y215
N
E
E
G
D
A
A
Y
Q
R
A
L
T
L
A
Frog
Xenopus laevis
NP_001089522
322
33988
F251
N
E
A
G
D
A
A
F
K
R
A
V
A
L
A
Zebra Danio
Brachydanio rerio
NP_997953
301
32308
H230
N
Q
T
G
D
A
A
H
R
E
A
L
S
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610805
299
31891
Y228
N
E
T
Q
D
A
A
Y
Q
Q
A
L
K
L
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34559
288
31153
V221
D
Q
V
V
G
E
A
V
K
L
G
E
K
I
A
Sea Urchin
Strong. purpuratus
XP_782821
303
32626
Y232
D
D
S
Q
E
A
A
Y
K
R
A
L
E
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
90.4
46.2
N.A.
85.4
34.5
N.A.
N.A.
72.5
53.1
62.1
N.A.
53.8
N.A.
32.1
48.8
Protein Similarity:
100
97.9
92.8
49.3
N.A.
89.5
49.3
N.A.
N.A.
82.1
68.6
75
N.A.
67.5
N.A.
49.3
64.6
P-Site Identity:
100
100
93.3
20
N.A.
80
26.6
N.A.
N.A.
86.6
73.3
53.3
N.A.
66.6
N.A.
13.3
46.6
P-Site Similarity:
100
100
93.3
20
N.A.
86.6
40
N.A.
N.A.
86.6
86.6
80
N.A.
73.3
N.A.
40
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
0
0
75
100
0
0
0
84
0
42
0
100
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
17
9
0
9
59
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
59
42
0
17
17
0
0
0
9
0
17
17
0
0
% E
% Phe:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
59
17
0
0
0
9
9
17
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
17
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
0
17
0
% I
% Lys:
0
0
0
0
0
0
0
0
25
0
0
0
25
0
0
% K
% Leu:
0
0
9
0
0
0
0
9
0
9
0
50
0
84
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
67
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
17
0
17
0
0
0
0
42
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
59
0
25
0
0
0
% R
% Ser:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% S
% Thr:
0
9
17
0
0
0
0
0
0
0
0
0
9
0
0
% T
% Val:
0
0
9
17
0
0
0
9
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _