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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PALB2 All Species: 11.52
Human Site: S209 Identified Species: 42.22
UniProt: Q86YC2 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86YC2 NP_078951.2 1186 131295 S209 L K S E L P D S P E P V T E I
Chimpanzee Pan troglodytes XP_510877 1186 131514 S209 L K S E L P D S P E P V T E I
Rhesus Macaque Macaca mulatta XP_001095453 1179 130327 S209 L K S E L P D S P E P V T E T
Dog Lupus familis XP_850671 1224 135310 S238 S M S D I P G S P S P V M E T
Cat Felis silvestris
Mouse Mus musculus Q3U0P1 1104 119079 F161 S Q E K E D Y F D T N S L A L
Rat Rattus norvegicus XP_215047 1110 120525 L167 D F F D T S S L V L P G R H Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414873 1173 127712 N205 Q N D A G S L N A F P S D L P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 90 68.8 N.A. 59.1 58.3 N.A. N.A. 29.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.3 93.3 76.3 N.A. 70.2 70.4 N.A. N.A. 47.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 46.6 N.A. 0 6.6 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 60 N.A. 20 13.3 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 15 0 0 0 0 15 0 0 0 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 15 29 0 15 43 0 15 0 0 0 15 0 0 % D
% Glu: 0 0 15 43 15 0 0 0 0 43 0 0 0 58 0 % E
% Phe: 0 15 15 0 0 0 0 15 0 15 0 0 0 0 0 % F
% Gly: 0 0 0 0 15 0 15 0 0 0 0 15 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % H
% Ile: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 29 % I
% Lys: 0 43 0 15 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 43 0 0 0 43 0 15 15 0 15 0 0 15 15 15 % L
% Met: 0 15 0 0 0 0 0 0 0 0 0 0 15 0 0 % M
% Asn: 0 15 0 0 0 0 0 15 0 0 15 0 0 0 0 % N
% Pro: 0 0 0 0 0 58 0 0 58 0 86 0 0 0 15 % P
% Gln: 15 15 0 0 0 0 0 0 0 0 0 0 0 0 15 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % R
% Ser: 29 0 58 0 0 29 15 58 0 15 0 29 0 0 0 % S
% Thr: 0 0 0 0 15 0 0 0 0 15 0 0 43 0 29 % T
% Val: 0 0 0 0 0 0 0 0 15 0 0 58 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _