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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DZIP1 All Species: 13.64
Human Site: S486 Identified Species: 30
UniProt: Q86YF9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86YF9 NP_055749.1 867 98664 S486 L H T L E T K S S L P M V H E
Chimpanzee Pan troglodytes XP_001138000 856 97433 S475 L H T L E T K S S L P M V H E
Rhesus Macaque Macaca mulatta XP_001085816 866 98762 S485 L H T S E T K S S L P M A Q E
Dog Lupus familis XP_853725 766 88505 G448 E D L K N S R G D Q Q K M L A
Cat Felis silvestris
Mouse Mus musculus Q8BMD2 852 97271 S470 T Q N L D G A S S L T M V H E
Rat Rattus norvegicus Q5XIA0 776 88007 Q456 N N P A W L K Q F R P I L E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512495 891 100705 K505 A P Q A L D P K S S P T V P E
Chicken Gallus gallus XP_416984 825 93959 E451 V H M L E P I E E L S E E E K
Frog Xenopus laevis NP_001087009 817 92677 S463 K P I A S S L S D V E A D V S
Zebra Danio Brachydanio rerio Q7T019 898 101709 D493 E L S E E D K D S S S I S E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799867 920 104880 S478 Y E V V E P R S S P P S R M T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 96.3 26.4 N.A. 67.3 28.6 N.A. 61.1 48.2 36.4 28.3 N.A. N.A. N.A. N.A. 24.5
Protein Similarity: 100 98 97.3 46.9 N.A. 77.7 47.2 N.A. 74.9 66.6 57.4 49.4 N.A. N.A. N.A. N.A. 44.2
P-Site Identity: 100 100 80 0 N.A. 53.3 13.3 N.A. 26.6 26.6 6.6 20 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 80 20 N.A. 60 40 N.A. 26.6 40 20 33.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 28 0 0 10 0 0 0 0 10 10 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 10 19 0 10 19 0 0 0 10 0 10 % D
% Glu: 19 10 0 10 55 0 0 10 10 0 10 10 10 28 46 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % G
% His: 0 37 0 0 0 0 0 0 0 0 0 0 0 28 0 % H
% Ile: 0 0 10 0 0 0 10 0 0 0 0 19 0 0 0 % I
% Lys: 10 0 0 10 0 0 46 10 0 0 0 10 0 0 10 % K
% Leu: 28 10 10 37 10 10 10 0 0 46 0 0 10 10 0 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 37 10 10 0 % M
% Asn: 10 10 10 0 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 19 10 0 0 19 10 0 0 10 55 0 0 10 0 % P
% Gln: 0 10 10 0 0 0 0 10 0 10 10 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 19 0 0 10 0 0 10 0 0 % R
% Ser: 0 0 10 10 10 19 0 55 64 19 19 10 10 0 19 % S
% Thr: 10 0 28 0 0 28 0 0 0 0 10 10 0 0 10 % T
% Val: 10 0 10 10 0 0 0 0 0 10 0 0 37 10 0 % V
% Trp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _