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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDSS2
All Species:
31.21
Human Site:
S174
Identified Species:
57.22
UniProt:
Q86YH6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86YH6
NP_065114.3
399
44129
S174
N
L
N
E
L
Q
S
S
D
G
P
L
K
D
M
Chimpanzee
Pan troglodytes
XP_001146753
399
44037
S174
N
L
N
E
L
Q
S
S
D
G
P
L
K
D
M
Rhesus Macaque
Macaca mulatta
XP_001090452
399
44007
S174
N
L
N
E
L
Q
S
S
D
G
P
L
K
D
M
Dog
Lupus familis
XP_539071
400
43839
S174
N
L
N
E
L
Q
S
S
D
G
P
L
K
D
M
Cat
Felis silvestris
Mouse
Mus musculus
Q33DR3
401
43962
S175
N
L
S
E
L
Q
S
S
D
G
P
L
K
D
M
Rat
Rattus norvegicus
Q5U2R1
401
44276
S175
N
L
S
E
L
Q
S
S
D
G
P
L
K
D
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511694
390
41913
S164
N
L
G
E
L
K
T
S
D
G
P
L
K
D
M
Chicken
Gallus gallus
XP_419804
379
41240
G163
P
L
K
D
M
Q
F
G
N
K
M
A
V
L
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002351
370
40730
G167
N
K
M
A
V
L
S
G
D
F
L
L
A
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649277
448
49427
S188
S
V
V
N
L
Q
S
S
T
Q
A
G
Q
D
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785706
562
60871
A267
N
L
L
N
L
D
P
A
T
G
P
I
N
V
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P18900
473
52541
S199
H
D
D
V
I
D
H
S
D
T
R
R
G
R
P
Red Bread Mold
Neurospora crassa
Q7S565
449
48454
R216
V
I
D
H
S
E
S
R
R
G
A
P
S
A
N
Conservation
Percent
Protein Identity:
100
99
98.7
91.5
N.A.
88.2
88
N.A.
62.6
73.9
N.A.
60.6
N.A.
36.6
N.A.
N.A.
33.1
Protein Similarity:
100
99.5
99.2
95.7
N.A.
92.5
92.5
N.A.
73.6
82.7
N.A.
76.1
N.A.
56.9
N.A.
N.A.
47.8
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
80
13.3
N.A.
26.6
N.A.
33.3
N.A.
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
33.3
N.A.
40
N.A.
60
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.1
29.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.8
50.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
8
0
0
16
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
16
8
0
16
0
0
70
0
0
0
0
62
0
% D
% Glu:
0
0
0
54
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
16
0
70
0
8
8
0
0
% G
% His:
8
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
8
8
0
0
8
0
0
0
8
0
0
54
0
0
% K
% Leu:
0
70
8
0
70
8
0
0
0
0
8
62
0
8
0
% L
% Met:
0
0
8
0
8
0
0
0
0
0
8
0
0
0
62
% M
% Asn:
70
0
31
16
0
0
0
0
8
0
0
0
8
8
8
% N
% Pro:
8
0
0
0
0
0
8
0
0
0
62
8
0
0
8
% P
% Gln:
0
0
0
0
0
62
0
0
0
8
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
8
0
8
8
0
8
0
% R
% Ser:
8
0
16
0
8
0
70
70
0
0
0
0
8
0
8
% S
% Thr:
0
0
0
0
0
0
8
0
16
8
0
0
0
0
0
% T
% Val:
8
8
8
8
8
0
0
0
0
0
0
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _