KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDSS2
All Species:
29.09
Human Site:
S378
Identified Species:
53.33
UniProt:
Q86YH6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86YH6
NP_065114.3
399
44129
S378
K
A
L
E
A
L
E
S
F
P
P
S
E
A
R
Chimpanzee
Pan troglodytes
XP_001146753
399
44037
S378
K
A
L
E
A
L
E
S
F
P
P
S
E
A
R
Rhesus Macaque
Macaca mulatta
XP_001090452
399
44007
S378
K
A
L
E
A
L
E
S
F
P
P
S
E
A
R
Dog
Lupus familis
XP_539071
400
43839
S379
K
A
L
E
A
L
E
S
F
P
P
S
E
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q33DR3
401
43962
S380
K
A
L
E
A
L
E
S
F
P
P
S
E
A
R
Rat
Rattus norvegicus
Q5U2R1
401
44276
S380
K
A
L
E
A
L
E
S
F
P
P
S
E
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511694
390
41913
H369
K
A
L
E
A
L
E
H
F
P
P
S
E
A
R
Chicken
Gallus gallus
XP_419804
379
41240
S358
R
A
L
A
A
L
E
S
F
P
P
S
E
A
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002351
370
40730
C350
K
A
L
E
A
M
K
C
F
P
P
S
D
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649277
448
49427
H428
A
A
L
A
V
L
Q
H
F
P
A
T
D
A
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785706
562
60871
A468
T
A
L
Q
G
L
S
A
F
P
A
S
D
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P18900
473
52541
S451
A
L
Q
N
L
R
D
S
L
P
E
S
D
A
R
Red Bread Mold
Neurospora crassa
Q7S565
449
48454
G427
K
A
I
E
A
I
S
G
F
P
D
S
E
A
K
Conservation
Percent
Protein Identity:
100
99
98.7
91.5
N.A.
88.2
88
N.A.
62.6
73.9
N.A.
60.6
N.A.
36.6
N.A.
N.A.
33.1
Protein Similarity:
100
99.5
99.2
95.7
N.A.
92.5
92.5
N.A.
73.6
82.7
N.A.
76.1
N.A.
56.9
N.A.
N.A.
47.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
86.6
N.A.
73.3
N.A.
46.6
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
93.3
N.A.
66.6
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.1
29.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.8
50.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
60
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
93
0
16
77
0
0
8
0
0
16
0
0
93
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
8
0
31
0
0
% D
% Glu:
0
0
0
70
0
0
62
0
0
0
8
0
70
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
93
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
70
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% K
% Leu:
0
8
85
0
8
77
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
100
70
0
0
0
0
% P
% Gln:
0
0
8
8
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
93
% R
% Ser:
0
0
0
0
0
0
16
62
0
0
0
93
0
8
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _