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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDSS2
All Species:
30.3
Human Site:
T251
Identified Species:
55.56
UniProt:
Q86YH6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86YH6
NP_065114.3
399
44129
T251
I
S
T
W
K
E
Q
T
F
L
S
H
G
A
L
Chimpanzee
Pan troglodytes
XP_001146753
399
44037
T251
I
S
T
W
K
E
Q
T
F
L
S
H
G
A
L
Rhesus Macaque
Macaca mulatta
XP_001090452
399
44007
T251
I
S
T
W
K
E
Q
T
F
L
S
H
G
A
L
Dog
Lupus familis
XP_539071
400
43839
T252
I
S
T
W
K
E
Q
T
F
L
S
H
G
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q33DR3
401
43962
T253
I
S
T
W
K
E
Q
T
F
L
S
H
C
A
L
Rat
Rattus norvegicus
Q5U2R1
401
44276
T253
I
S
T
W
K
E
Q
T
F
L
S
H
C
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511694
390
41913
T242
I
S
A
W
K
K
Q
T
F
L
S
H
S
A
L
Chicken
Gallus gallus
XP_419804
379
41240
S235
E
Q
V
F
L
S
H
S
A
L
L
A
K
S
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002351
370
40730
M239
A
K
S
C
Q
A
A
M
K
L
A
R
H
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649277
448
49427
N302
E
E
E
W
E
C
R
N
I
L
N
A
G
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785706
562
60871
V347
F
L
D
W
E
R
Y
V
Y
L
S
S
G
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P18900
473
52541
V280
N
G
H
K
L
L
P
V
P
S
K
K
L
E
V
Red Bread Mold
Neurospora crassa
Q7S565
449
48454
T297
L
T
Y
Y
L
Q
K
T
Y
L
K
T
A
S
L
Conservation
Percent
Protein Identity:
100
99
98.7
91.5
N.A.
88.2
88
N.A.
62.6
73.9
N.A.
60.6
N.A.
36.6
N.A.
N.A.
33.1
Protein Similarity:
100
99.5
99.2
95.7
N.A.
92.5
92.5
N.A.
73.6
82.7
N.A.
76.1
N.A.
56.9
N.A.
N.A.
47.8
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
80
6.6
N.A.
6.6
N.A.
26.6
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
26.6
N.A.
26.6
N.A.
53.3
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.1
29.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.8
50.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
8
8
0
8
0
8
16
8
54
0
% A
% Cys:
0
0
0
8
0
8
0
0
0
0
0
0
16
0
8
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
16
8
8
0
16
47
0
0
0
0
0
0
0
8
0
% E
% Phe:
8
0
0
8
0
0
0
0
54
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
47
0
0
% G
% His:
0
0
8
0
0
0
8
0
0
0
0
54
8
0
0
% H
% Ile:
54
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
8
0
8
54
8
8
0
8
0
16
8
8
0
0
% K
% Leu:
8
8
0
0
24
8
0
0
0
93
8
0
8
0
77
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
0
0
8
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
8
8
54
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
8
0
0
0
0
8
0
0
0
% R
% Ser:
0
54
8
0
0
8
0
8
0
8
62
8
8
24
0
% S
% Thr:
0
8
47
0
0
0
0
62
0
0
0
8
0
8
8
% T
% Val:
0
0
8
0
0
0
0
16
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
70
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
0
8
0
16
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _