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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THNSL2
All Species:
21.21
Human Site:
S349
Identified Species:
46.67
UniProt:
Q86YJ6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86YJ6
NP_060741.3
484
54188
S349
E
Q
F
E
R
T
Q
S
V
N
L
P
K
E
L
Chimpanzee
Pan troglodytes
XP_515606
559
62215
S424
E
Q
F
E
R
T
Q
S
V
N
L
P
K
E
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532965
484
53876
S349
E
Q
F
E
R
T
Q
S
M
S
L
P
K
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80W22
483
54170
S349
E
Q
F
E
R
T
Q
S
L
Q
L
P
K
D
L
Rat
Rattus norvegicus
Q5M7T9
485
54119
S349
E
Q
F
E
R
T
Q
S
L
H
L
P
K
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511943
516
58195
R376
E
K
F
D
K
T
K
R
V
K
L
P
E
I
L
Chicken
Gallus gallus
XP_420866
494
54438
S349
E
Q
F
T
V
S
K
S
L
K
L
P
E
G
L
Frog
Xenopus laevis
Q5XH07
472
53326
K338
S
H
I
K
E
M
M
K
E
F
Q
E
K
K
R
Zebra Danio
Brachydanio rerio
Q2YDP8
476
53062
L341
D
G
L
M
V
K
S
L
M
E
E
F
Q
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793160
412
45730
K278
M
D
S
V
L
W
K
K
I
R
E
T
V
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P16120
514
57456
W366
A
G
E
I
V
N
N
W
F
Q
E
L
K
T
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86
N.A.
86.5
N.A.
83.4
83.9
N.A.
67
66.8
60.5
53.5
N.A.
N.A.
N.A.
N.A.
37.4
Protein Similarity:
100
86.4
N.A.
91.5
N.A.
91.1
92.1
N.A.
80.4
79.9
77
70
N.A.
N.A.
N.A.
N.A.
54.7
P-Site Identity:
100
100
N.A.
86.6
N.A.
80
80
N.A.
46.6
46.6
6.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
100
N.A.
80
73.3
20
26.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
10
0
0
0
0
0
0
0
0
0
19
0
% D
% Glu:
64
0
10
46
10
0
0
0
10
10
28
10
19
28
0
% E
% Phe:
0
0
64
0
0
0
0
0
10
10
0
10
0
0
0
% F
% Gly:
0
19
0
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
10
0
0
0
0
10
0
0
0
0
10
0
% I
% Lys:
0
10
0
10
10
10
28
19
0
19
0
0
64
19
0
% K
% Leu:
0
0
10
0
10
0
0
10
28
0
64
10
0
0
64
% L
% Met:
10
0
0
10
0
10
10
0
19
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
10
0
0
19
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
64
0
0
0
% P
% Gln:
0
55
0
0
0
0
46
0
0
19
10
0
10
0
0
% Q
% Arg:
0
0
0
0
46
0
0
10
0
10
0
0
0
0
10
% R
% Ser:
10
0
10
0
0
10
10
55
0
10
0
0
0
10
10
% S
% Thr:
0
0
0
10
0
55
0
0
0
0
0
10
0
10
10
% T
% Val:
0
0
0
10
28
0
0
0
28
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _