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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HOMER1 All Species: 24.85
Human Site: S237 Identified Species: 60.74
UniProt: Q86YM7 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86YM7 NP_004263.1 354 40277 S237 T E L E C V S S Q A N A V H T
Chimpanzee Pan troglodytes XP_526882 346 39501 T236 S Q A N A V H T H K T E L N Q
Rhesus Macaque Macaca mulatta XP_001109003 342 39090 T232 S Q A N A V H T H K T E L N Q
Dog Lupus familis XP_849709 354 40244 S237 T E L E C V S S Q A N A V H T
Cat Felis silvestris
Mouse Mus musculus Q9Z2Y3 366 41394 S249 T E L E C V S S Q A N A V H S
Rat Rattus norvegicus Q9Z214 366 41286 S249 T E L E C V S S Q A N A V H S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517780 262 29833 I161 K T E L N Q T I Q D L E A T L
Chicken Gallus gallus XP_424768 377 43112 S260 T E L E C V S S Q A N A V H T
Frog Xenopus laevis NP_001089052 355 40398 N238 S E L E C M S N Q A N A V Q S
Zebra Danio Brachydanio rerio XP_002662151 398 45065 S281 S E L E S Q S S Q T N V I K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.7 96 99.7 N.A. 95.6 94.2 N.A. 71.7 91.5 90.6 67 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.7 96.6 100 N.A. 96.7 96.4 N.A. 73.1 92.5 97.1 76.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 6.6 100 N.A. 93.3 93.3 N.A. 6.6 100 66.6 46.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 40 40 100 N.A. 100 100 N.A. 13.3 100 93.3 66.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 0 20 0 0 0 0 60 0 60 10 0 0 % A
% Cys: 0 0 0 0 60 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 70 10 70 0 0 0 0 0 0 0 30 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 20 0 20 0 0 0 0 50 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 20 0 0 0 10 0 % K
% Leu: 0 0 70 10 0 0 0 0 0 0 10 0 20 0 10 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 20 10 0 0 10 0 0 70 0 0 20 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 20 0 0 0 20 0 0 80 0 0 0 0 10 20 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 40 0 0 0 10 0 70 60 0 0 0 0 0 0 40 % S
% Thr: 50 10 0 0 0 0 10 20 0 10 20 0 0 10 30 % T
% Val: 0 0 0 0 0 70 0 0 0 0 0 10 60 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _