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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HOMER1
All Species:
25.15
Human Site:
T259
Identified Species:
61.48
UniProt:
Q86YM7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86YM7
NP_004263.1
354
40277
T259
T
I
Q
E
L
E
E
T
L
K
L
K
E
E
E
Chimpanzee
Pan troglodytes
XP_526882
346
39501
E258
T
L
K
L
K
E
E
E
I
E
R
L
K
Q
E
Rhesus Macaque
Macaca mulatta
XP_001109003
342
39090
E254
T
L
K
V
K
E
E
E
I
E
R
L
K
Q
E
Dog
Lupus familis
XP_849709
354
40244
T259
T
I
Q
E
L
E
E
T
L
K
V
K
E
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2Y3
366
41394
T271
T
V
Q
E
L
E
E
T
L
K
V
K
E
E
E
Rat
Rattus norvegicus
Q9Z214
366
41286
T271
T
V
Q
E
L
E
E
T
L
K
V
K
E
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517780
262
29833
D183
E
R
L
R
Q
E
I
D
N
A
R
E
L
Q
A
Chicken
Gallus gallus
XP_424768
377
43112
T282
T
I
Q
E
L
E
S
T
L
K
K
K
E
E
E
Frog
Xenopus laevis
NP_001089052
355
40398
T260
K
I
Q
E
L
E
T
T
L
K
K
K
E
E
E
Zebra Danio
Brachydanio rerio
XP_002662151
398
45065
T303
T
I
E
E
L
E
C
T
L
R
A
K
E
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
96
99.7
N.A.
95.6
94.2
N.A.
71.7
91.5
90.6
67
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.7
96.6
100
N.A.
96.7
96.4
N.A.
73.1
92.5
97.1
76.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
26.6
93.3
N.A.
86.6
86.6
N.A.
6.6
86.6
80
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
66.6
100
N.A.
100
100
N.A.
20
86.6
80
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
10
0
10
70
0
100
60
20
0
20
0
10
70
70
90
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
50
0
0
0
0
10
0
20
0
0
0
0
0
0
% I
% Lys:
10
0
20
0
20
0
0
0
0
60
20
70
20
0
0
% K
% Leu:
0
20
10
10
70
0
0
0
70
0
10
20
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
60
0
10
0
0
0
0
0
0
0
0
30
0
% Q
% Arg:
0
10
0
10
0
0
0
0
0
10
30
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% S
% Thr:
80
0
0
0
0
0
10
70
0
0
0
0
0
0
0
% T
% Val:
0
20
0
10
0
0
0
0
0
0
30
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _