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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPARGC1B
All Species:
12.12
Human Site:
T99
Identified Species:
38.1
UniProt:
Q86YN6
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86YN6
NP_573570.2
1023
113222
T99
L
L
A
E
L
T
K
T
L
D
D
I
P
E
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105289
798
91073
Dog
Lupus familis
XP_546308
1081
118847
K152
A
L
L
A
A
L
T
K
T
L
D
D
I
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHJ7
1014
112057
T99
L
L
A
A
L
T
K
T
L
D
D
I
P
E
D
Rat
Rattus norvegicus
Q811R2
1010
111570
T99
L
L
A
A
L
T
K
T
L
D
D
I
P
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506867
1014
111303
T121
F
L
A
A
L
T
K
T
L
D
D
I
Q
E
D
Chicken
Gallus gallus
XP_414479
996
108812
M93
L
T
E
T
L
D
D
M
Q
G
D
D
V
G
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002664439
495
55379
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
27.5
81.5
N.A.
78.6
78.1
N.A.
56.5
49.9
N.A.
22.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
41.3
85.7
N.A.
85.7
85.2
N.A.
67.1
61.1
N.A.
32.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
0
13.3
N.A.
93.3
93.3
N.A.
80
20
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
0
20
N.A.
93.3
93.3
N.A.
80
20
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
50
50
13
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
13
13
0
0
50
75
25
0
0
50
% D
% Glu:
0
0
13
13
0
0
0
0
0
0
0
0
0
50
13
% E
% Phe:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
13
0
0
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
50
13
0
0
% I
% Lys:
0
0
0
0
0
0
50
13
0
0
0
0
0
0
0
% K
% Leu:
50
63
13
0
63
13
0
0
50
13
0
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
38
13
0
% P
% Gln:
0
0
0
0
0
0
0
0
13
0
0
0
13
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
13
0
13
0
50
13
50
13
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _