Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAB43 All Species: 19.39
Human Site: Y15 Identified Species: 28.44
UniProt: Q86YS6 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86YS6 NP_940892.1 212 23339 Y15 P G D P D E Q Y D F L F K L V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094209 269 29623 Y15 P G D P D E Q Y D F L F K L V
Dog Lupus familis XP_539883 217 24593 F14 S R A A D E N F D Y L F K I I
Cat Felis silvestris
Mouse Mus musculus Q8CG50 210 23245 Y13 P G D Q D E H Y D F L F K L V
Rat Rattus norvegicus Q53B90 210 23211 Y13 P G D Q D E H Y D F L F K L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505416 151 16977
Chicken Gallus gallus Q5ZJN2 216 24420 Y8 M G N R D D E Y D Y L F K V V
Frog Xenopus laevis Q32NQ0 213 24055 F12 G S L E D D P F D F L F K I I
Zebra Danio Brachydanio rerio NP_001038812 208 22961 Y10 L L D S D D S Y D L V F K I V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523970 219 25031 F18 A L P N E E H F D F L F K I V
Honey Bee Apis mellifera XP_624576 219 25203 F17 I T T N D E N F D Y L F K I V
Nematode Worm Caenorhab. elegans NP_502576 210 23303 F11 D D G F D Y L F K I V L V G D
Sea Urchin Strong. purpuratus XP_794320 208 23436 F11 V D S S D E T F D Y L F K I V
Poplar Tree Populus trichocarpa
Maize Zea mays P16976 208 23293 F9 S N E F D Y L F K L L L I G D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZRE2 205 22706 F9 S N E Y D Y L F K L L L I G D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P33723 203 22458 F9 N P E Y D Y L F K L L L I G D
Conservation
Percent
Protein Identity: 100 N.A. 76.5 52.5 N.A. 91.5 91.9 N.A. 59.9 43.9 54.9 71.2 N.A. 51.5 50.6 53.2 58.4
Protein Similarity: 100 N.A. 76.9 71.4 N.A. 94.8 95.2 N.A. 67.4 63.8 74.6 82.5 N.A. 68 69.8 67.4 75.9
P-Site Identity: 100 N.A. 100 40 N.A. 86.6 86.6 N.A. 0 53.3 40 46.6 N.A. 46.6 46.6 6.6 46.6
P-Site Similarity: 100 N.A. 100 66.6 N.A. 86.6 86.6 N.A. 0 86.6 66.6 66.6 N.A. 66.6 66.6 20 66.6
Percent
Protein Identity: N.A. 45.7 N.A. 47.1 N.A. 42.9
Protein Similarity: N.A. 66 N.A. 66.5 N.A. 64.6
P-Site Identity: N.A. 13.3 N.A. 13.3 N.A. 13.3
P-Site Similarity: N.A. 26.6 N.A. 26.6 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 7 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 13 32 0 88 19 0 0 69 0 0 0 0 0 25 % D
% Glu: 0 0 19 7 7 50 7 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 13 0 0 0 57 0 38 0 69 0 0 0 % F
% Gly: 7 32 7 0 0 0 0 0 0 0 0 0 0 25 0 % G
% His: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 0 0 0 0 7 0 0 19 38 13 % I
% Lys: 0 0 0 0 0 0 0 0 25 0 0 0 69 0 0 % K
% Leu: 7 13 7 0 0 0 25 0 0 25 82 25 0 25 0 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 13 7 13 0 0 13 0 0 0 0 0 0 0 0 % N
% Pro: 25 7 7 13 0 0 7 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 13 0 0 13 0 0 0 0 0 0 0 0 % Q
% Arg: 0 7 0 7 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 19 7 7 13 0 0 7 0 0 0 0 0 0 0 0 % S
% Thr: 0 7 7 0 0 0 7 0 0 0 0 0 0 0 0 % T
% Val: 7 0 0 0 0 0 0 0 0 0 13 0 7 7 57 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 13 0 25 0 38 0 25 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _