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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC13A5
All Species:
16.36
Human Site:
S381
Identified Species:
30
UniProt:
Q86YT5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86YT5
NP_808218.1
568
63062
S381
K
P
K
F
N
F
R
S
Q
T
E
E
E
R
K
Chimpanzee
Pan troglodytes
XP_511987
475
52630
K306
S
Q
T
E
E
E
R
K
T
P
F
Y
P
P
P
Rhesus Macaque
Macaca mulatta
XP_001106342
566
61315
P369
F
P
G
L
T
Q
D
P
E
N
P
G
K
L
K
Dog
Lupus familis
XP_848573
571
63049
S384
R
P
Q
F
N
F
R
S
Q
T
E
E
E
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q67BT3
572
63805
S385
K
P
K
F
N
F
S
S
Q
T
E
E
E
R
K
Rat
Rattus norvegicus
Q8CJ44
572
63860
R385
K
P
K
F
N
F
S
R
Q
T
E
E
E
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511671
727
80080
S377
K
P
Q
F
N
F
R
S
Q
T
D
E
E
W
K
Chicken
Gallus gallus
XP_415923
587
64650
S395
P
K
F
I
G
W
N
S
S
M
S
D
T
E
Q
Frog
Xenopus laevis
NP_001086781
586
64942
K394
K
P
K
F
G
C
C
K
A
R
N
S
F
D
L
Zebra Danio
Brachydanio rerio
NP_001136038
578
63601
R390
P
P
R
L
C
F
W
R
T
E
S
F
D
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVT2
590
65567
T397
Y
A
F
L
R
Y
C
T
R
R
G
G
P
V
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93655
582
64168
S382
L
P
S
S
R
G
S
S
E
Q
R
K
A
S
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LG88
540
58080
I368
M
M
A
T
L
L
F
I
I
P
S
N
I
K
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83
49.1
84.4
N.A.
74.4
77.2
N.A.
54
62.8
62.7
61.9
N.A.
36.4
N.A.
41.4
N.A.
Protein Similarity:
100
83.4
67.4
92.2
N.A.
85.6
87.7
N.A.
65.3
77
78.3
79.2
N.A.
58.9
N.A.
61.3
N.A.
P-Site Identity:
100
6.6
13.3
86.6
N.A.
93.3
86.6
N.A.
80
6.6
26.6
13.3
N.A.
0
N.A.
13.3
N.A.
P-Site Similarity:
100
6.6
26.6
100
N.A.
93.3
86.6
N.A.
93.3
26.6
26.6
26.6
N.A.
20
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
0
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
8
8
16
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
8
8
8
8
0
% D
% Glu:
0
0
0
8
8
8
0
0
16
8
31
39
39
8
0
% E
% Phe:
8
0
16
47
0
47
8
0
0
0
8
8
8
0
0
% F
% Gly:
0
0
8
0
16
8
0
0
0
0
8
16
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
8
8
0
0
0
8
0
0
% I
% Lys:
39
8
31
0
0
0
0
16
0
0
0
8
8
8
54
% K
% Leu:
8
0
0
24
8
8
0
0
0
0
0
0
0
8
8
% L
% Met:
8
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
39
0
8
0
0
8
8
8
0
0
0
% N
% Pro:
16
70
0
0
0
0
0
8
0
16
8
0
16
8
16
% P
% Gln:
0
8
16
0
0
8
0
0
39
8
0
0
0
0
8
% Q
% Arg:
8
0
8
0
16
0
31
16
8
16
8
0
0
31
0
% R
% Ser:
8
0
8
8
0
0
24
47
8
0
24
8
0
8
8
% S
% Thr:
0
0
8
8
8
0
0
8
16
39
0
0
8
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
8
8
0
0
0
0
0
0
8
0
% W
% Tyr:
8
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _