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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MIB1 All Species: 22.73
Human Site: S398 Identified Species: 45.45
UniProt: Q86YT6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86YT6 NP_065825.1 1006 110136 S398 T Y N P A A V S K V A S A G S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092086 1006 110131 S398 T Y N P A A V S K V A S A G S
Dog Lupus familis XP_547643 1006 109709 S398 T Y N P A A V S K V A S A G S
Cat Felis silvestris
Mouse Mus musculus Q80SY4 1006 110069 S398 T Y N P A A V S K V A P A G S
Rat Rattus norvegicus Q68LP1 971 105524 E407 D A N L G V A E R A R E N K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506970 730 80610 N271 S G N R W T F N P A V L T K A
Chicken Gallus gallus Q5ZIJ9 954 106321 E421 S T L I T V L E K L L S Q K T
Frog Xenopus laevis Q6GNY1 1011 110670 S398 T Y N P A A V S R V A S V G S
Zebra Danio Brachydanio rerio Q804S5 1030 112669 T398 T Y N P A A V T K V A P A G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUX2 1226 129854 S488 A V C K V A S S T A S D G S C
Honey Bee Apis mellifera XP_394129 580 63018 D121 C S I C Y H G D K H H L R H R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_779955 570 63000 L111 A E C P N Y D L C S V C Y H G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.9 93 N.A. 99.3 39.7 N.A. 63.7 39 95 91.5 N.A. 57 44.8 N.A. 41.4
Protein Similarity: 100 N.A. 100 94.2 N.A. 99.6 57.3 N.A. 67.1 58.4 97.1 95.8 N.A. 67.4 50 N.A. 47.7
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 13.3 N.A. 6.6 13.3 86.6 86.6 N.A. 13.3 6.6 N.A. 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 20 N.A. 26.6 40 93.3 93.3 N.A. 20 6.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 9 0 0 50 59 9 0 0 25 50 0 42 0 9 % A
% Cys: 9 0 17 9 0 0 0 0 9 0 0 9 0 0 9 % C
% Asp: 9 0 0 0 0 0 9 9 0 0 0 9 0 0 0 % D
% Glu: 0 9 0 0 0 0 0 17 0 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 9 0 9 0 0 0 0 0 9 50 9 % G
% His: 0 0 0 0 0 9 0 0 0 9 9 0 0 17 0 % H
% Ile: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 9 0 0 0 0 59 0 0 0 0 25 0 % K
% Leu: 0 0 9 9 0 0 9 9 0 9 9 17 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 67 0 9 0 0 9 0 0 0 0 9 0 0 % N
% Pro: 0 0 0 59 0 0 0 0 9 0 0 17 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % Q
% Arg: 0 0 0 9 0 0 0 0 17 0 9 0 9 0 9 % R
% Ser: 17 9 0 0 0 0 9 50 0 9 9 42 0 9 59 % S
% Thr: 50 9 0 0 9 9 0 9 9 0 0 0 9 0 9 % T
% Val: 0 9 0 0 9 17 50 0 0 50 17 0 9 0 0 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 50 0 0 9 9 0 0 0 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _