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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MIB1 All Species: 26.97
Human Site: Y125 Identified Species: 53.94
UniProt: Q86YT6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86YT6 NP_065825.1 1006 110136 Y125 H H L R H R F Y R I T T P G S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092086 1006 110131 Y125 H H L R H R F Y R I T T P G S
Dog Lupus familis XP_547643 1006 109709 Y125 H H L R H R F Y R I T T P G S
Cat Felis silvestris
Mouse Mus musculus Q80SY4 1006 110069 Y125 H H L R H R F Y R I T T P G S
Rat Rattus norvegicus Q68LP1 971 105524 E131 H D L T H A F E R Y E T S H S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506970 730 80610 K43 C D D L D C I K H D G T M C D
Chicken Gallus gallus Q5ZIJ9 954 106321 E131 H D L S H A F E R Y E T A H S
Frog Xenopus laevis Q6GNY1 1011 110670 Y125 H H L R H R F Y R I T T P G S
Zebra Danio Brachydanio rerio Q804S5 1030 112669 Y125 H H L R H R F Y R I T T P G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUX2 1226 129854 Y219 H H L R H R F Y R I T T P G G
Honey Bee Apis mellifera XP_394129 580 63018
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_779955 570 63000
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.9 93 N.A. 99.3 39.7 N.A. 63.7 39 95 91.5 N.A. 57 44.8 N.A. 41.4
Protein Similarity: 100 N.A. 100 94.2 N.A. 99.6 57.3 N.A. 67.1 58.4 97.1 95.8 N.A. 67.4 50 N.A. 47.7
P-Site Identity: 100 N.A. 100 100 N.A. 100 46.6 N.A. 6.6 46.6 100 100 N.A. 93.3 0 N.A. 0
P-Site Similarity: 100 N.A. 100 100 N.A. 100 46.6 N.A. 6.6 46.6 100 100 N.A. 93.3 0 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 17 0 0 0 0 0 0 9 0 0 % A
% Cys: 9 0 0 0 0 9 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 25 9 0 9 0 0 0 0 9 0 0 0 0 9 % D
% Glu: 0 0 0 0 0 0 0 17 0 0 17 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 75 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 9 0 0 59 9 % G
% His: 75 59 0 0 75 0 0 0 9 0 0 0 0 17 0 % H
% Ile: 0 0 0 0 0 0 9 0 0 59 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % K
% Leu: 0 0 75 9 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 59 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 59 0 59 0 0 75 0 0 0 0 0 0 % R
% Ser: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 67 % S
% Thr: 0 0 0 9 0 0 0 0 0 0 59 84 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 59 0 17 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _