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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGK223 All Species: 1.52
Human Site: S552 Identified Species: 4.17
UniProt: Q86YV5 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86YV5 NP_001074295 1406 149688 S552 P P K L S K S S P V G S P V S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094718 1322 141203 P538 L S D P S R C P Q P V T S A L
Dog Lupus familis XP_540000 1393 147853 L523 K P A I P P K L S K S S P G G
Cat Felis silvestris
Mouse Mus musculus Q571I4 1179 126621 R437 E L S Q S W G R E L E N G T A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507039 1758 193149 A846 P L S K P V G A N P S K P V T
Chicken Gallus gallus XP_420588 1313 142360 A545 Q L L P R S C A D A S T F R T
Frog Xenopus laevis NP_001082542 1282 142382 L528 S S Q K K E S L E V N D R C L
Zebra Danio Brachydanio rerio XP_001921602 1695 184654 S834 P F P P V R S S S S P Y H S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001177956 680 74357
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 87.4 81.2 N.A. 66.4 N.A. N.A. 24.3 49.9 42.2 27.6 N.A. N.A. N.A. N.A. 21.3
Protein Similarity: 100 N.A. 89.4 85.6 N.A. 70.7 N.A. N.A. 38.5 60.3 55.3 41.1 N.A. N.A. N.A. N.A. 31.2
P-Site Identity: 100 N.A. 6.6 20 N.A. 6.6 N.A. N.A. 20 0 13.3 26.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 N.A. 20 26.6 N.A. 26.6 N.A. N.A. 33.3 20 26.6 33.3 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 0 0 0 23 0 12 0 0 0 12 12 % A
% Cys: 0 0 0 0 0 0 23 0 0 0 0 0 0 12 0 % C
% Asp: 0 0 12 0 0 0 0 0 12 0 0 12 0 0 0 % D
% Glu: 12 0 0 0 0 12 0 0 23 0 12 0 0 0 0 % E
% Phe: 0 12 0 0 0 0 0 0 0 0 0 0 12 0 0 % F
% Gly: 0 0 0 0 0 0 23 0 0 0 12 0 12 12 12 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % H
% Ile: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 12 0 12 23 12 12 12 0 0 12 0 12 0 0 0 % K
% Leu: 12 34 12 12 0 0 0 23 0 12 0 0 0 0 23 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 12 0 12 12 0 0 0 % N
% Pro: 34 23 12 34 23 12 0 12 12 23 12 0 34 0 0 % P
% Gln: 12 0 12 12 0 0 0 0 12 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 12 23 0 12 0 0 0 0 12 12 0 % R
% Ser: 12 23 23 0 34 12 34 23 23 12 34 23 12 12 23 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 23 0 12 23 % T
% Val: 0 0 0 0 12 12 0 0 0 23 12 0 0 23 0 % V
% Trp: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _