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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGK223
All Species:
4.55
Human Site:
S581
Identified Species:
12.5
UniProt:
Q86YV5
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86YV5
NP_001074295
1406
149688
S581
S
D
G
S
C
G
G
S
S
I
G
P
Q
P
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094718
1322
141203
E567
Q
C
R
I
E
E
E
E
E
V
E
Q
E
L
L
Dog
Lupus familis
XP_540000
1393
147853
T552
E
G
S
S
S
G
G
T
G
P
Q
A
S
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q571I4
1179
126621
S466
D
G
T
S
G
Q
N
S
K
T
N
S
G
M
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507039
1758
193149
S875
F
P
P
P
R
S
T
S
S
P
Y
H
A
S
N
Chicken
Gallus gallus
XP_420588
1313
142360
G574
E
S
S
R
G
L
A
G
S
P
Y
D
R
R
Q
Frog
Xenopus laevis
NP_001082542
1282
142382
E557
S
K
Q
C
K
I
D
E
E
E
E
E
E
A
S
Zebra Danio
Brachydanio rerio
XP_001921602
1695
184654
T863
A
K
S
T
D
G
E
T
S
P
G
A
E
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177956
680
74357
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87.4
81.2
N.A.
66.4
N.A.
N.A.
24.3
49.9
42.2
27.6
N.A.
N.A.
N.A.
N.A.
21.3
Protein Similarity:
100
N.A.
89.4
85.6
N.A.
70.7
N.A.
N.A.
38.5
60.3
55.3
41.1
N.A.
N.A.
N.A.
N.A.
31.2
P-Site Identity:
100
N.A.
0
20
N.A.
13.3
N.A.
N.A.
13.3
6.6
6.6
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
13.3
26.6
N.A.
13.3
N.A.
N.A.
13.3
13.3
13.3
46.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
12
0
0
0
0
23
12
12
0
% A
% Cys:
0
12
0
12
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
12
0
0
12
0
12
0
0
0
0
12
0
0
0
% D
% Glu:
23
0
0
0
12
12
23
23
23
12
23
12
34
0
0
% E
% Phe:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
23
12
0
23
34
23
12
12
0
23
0
12
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% H
% Ile:
0
0
0
12
0
12
0
0
0
12
0
0
0
0
0
% I
% Lys:
0
23
0
0
12
0
0
0
12
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
12
0
0
0
0
0
0
0
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
12
0
0
0
12
% N
% Pro:
0
12
12
12
0
0
0
0
0
45
0
12
0
12
12
% P
% Gln:
12
0
12
0
0
12
0
0
0
0
12
12
12
0
12
% Q
% Arg:
0
0
12
12
12
0
0
0
0
0
0
0
12
12
23
% R
% Ser:
23
12
34
34
12
12
0
34
45
0
0
12
12
23
23
% S
% Thr:
0
0
12
12
0
0
12
23
0
12
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
23
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _