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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGK223
All Species:
0.91
Human Site:
S621
Identified Species:
2.5
UniProt:
Q86YV5
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86YV5
NP_001074295
1406
149688
S621
Q
P
A
A
S
S
A
S
E
Q
R
R
P
R
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094718
1322
141203
Q607
P
T
D
G
S
S
G
Q
N
S
K
V
G
T
G
Dog
Lupus familis
XP_540000
1393
147853
D592
A
A
T
S
S
A
L
D
Q
R
R
P
R
Y
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q571I4
1179
126621
K506
P
K
S
R
H
L
L
K
M
N
K
S
S
S
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507039
1758
193149
A915
H
P
E
G
R
R
A
A
D
A
K
P
K
R
W
Chicken
Gallus gallus
XP_420588
1313
142360
A614
E
L
S
T
H
P
W
A
V
G
A
E
S
G
R
Frog
Xenopus laevis
NP_001082542
1282
142382
S597
S
S
V
E
E
Q
K
S
R
K
G
M
S
K
S
Zebra Danio
Brachydanio rerio
XP_001921602
1695
184654
R903
E
Q
K
E
K
M
E
R
E
K
E
K
G
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177956
680
74357
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87.4
81.2
N.A.
66.4
N.A.
N.A.
24.3
49.9
42.2
27.6
N.A.
N.A.
N.A.
N.A.
21.3
Protein Similarity:
100
N.A.
89.4
85.6
N.A.
70.7
N.A.
N.A.
38.5
60.3
55.3
41.1
N.A.
N.A.
N.A.
N.A.
31.2
P-Site Identity:
100
N.A.
13.3
13.3
N.A.
0
N.A.
N.A.
20
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
20
40
N.A.
13.3
N.A.
N.A.
46.6
20
20
33.3
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
12
12
0
12
23
23
0
12
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
0
12
12
0
0
0
0
0
12
% D
% Glu:
23
0
12
23
12
0
12
0
23
0
12
12
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
0
23
0
0
12
0
0
12
12
0
23
12
12
% G
% His:
12
0
0
0
23
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
12
0
12
0
12
12
0
23
34
12
12
23
0
% K
% Leu:
0
12
0
0
0
12
23
0
0
0
0
0
0
0
12
% L
% Met:
0
0
0
0
0
12
0
0
12
0
0
12
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
12
0
0
0
0
0
% N
% Pro:
23
23
0
0
0
12
0
0
0
0
0
23
12
0
0
% P
% Gln:
12
12
0
0
0
12
0
12
12
12
0
0
0
0
12
% Q
% Arg:
0
0
0
12
12
12
0
12
12
12
23
12
12
23
12
% R
% Ser:
12
12
23
12
34
23
0
23
0
12
0
12
34
12
12
% S
% Thr:
0
12
12
12
0
0
0
0
0
0
0
0
0
12
0
% T
% Val:
0
0
12
0
0
0
0
0
12
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
12
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _