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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGK223 All Species: 5.45
Human Site: S651 Identified Species: 15
UniProt: Q86YV5 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86YV5 NP_001074295 1406 149688 S651 E V E Q E L L S H S W G R E T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094718 1322 141203 R645 P P P P P K S R H L L K M N K
Dog Lupus familis XP_540000 1393 147853 S621 E V E Q E L L S Q S W G R E L
Cat Felis silvestris
Mouse Mus musculus Q571I4 1179 126621 V534 P S F R G A H V S F T T G S T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507039 1758 193149 F986 N E K P S I I F M Y R C E P E
Chicken Gallus gallus XP_420588 1313 142360 S644 A G I S K S L S F S F D F P K
Frog Xenopus laevis NP_001082542 1282 142382 P626 Y H A S Q P P P P P P K K Q T
Zebra Danio Brachydanio rerio XP_001921602 1695 184654 I947 P L Q K P T I I F T Y K S E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001177956 680 74357 F35 N S L E R L E F I N A Y R G Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 87.4 81.2 N.A. 66.4 N.A. N.A. 24.3 49.9 42.2 27.6 N.A. N.A. N.A. N.A. 21.3
Protein Similarity: 100 N.A. 89.4 85.6 N.A. 70.7 N.A. N.A. 38.5 60.3 55.3 41.1 N.A. N.A. N.A. N.A. 31.2
P-Site Identity: 100 N.A. 6.6 86.6 N.A. 6.6 N.A. N.A. 0 20 6.6 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 N.A. 6.6 86.6 N.A. 13.3 N.A. N.A. 20 33.3 26.6 53.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 12 0 0 12 0 0 0 0 12 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % D
% Glu: 23 12 23 12 23 0 12 0 0 0 0 0 12 34 12 % E
% Phe: 0 0 12 0 0 0 0 23 23 12 12 0 12 0 0 % F
% Gly: 0 12 0 0 12 0 0 0 0 0 0 23 12 12 0 % G
% His: 0 12 0 0 0 0 12 0 23 0 0 0 0 0 0 % H
% Ile: 0 0 12 0 0 12 23 12 12 0 0 0 0 0 0 % I
% Lys: 0 0 12 12 12 12 0 0 0 0 0 34 12 0 23 % K
% Leu: 0 12 12 0 0 34 34 0 0 12 12 0 0 0 12 % L
% Met: 0 0 0 0 0 0 0 0 12 0 0 0 12 0 0 % M
% Asn: 23 0 0 0 0 0 0 0 0 12 0 0 0 12 0 % N
% Pro: 34 12 12 23 23 12 12 12 12 12 12 0 0 23 0 % P
% Gln: 0 0 12 23 12 0 0 0 12 0 0 0 0 12 12 % Q
% Arg: 0 0 0 12 12 0 0 12 0 0 12 0 34 0 0 % R
% Ser: 0 23 0 23 12 12 12 34 12 34 0 0 12 12 12 % S
% Thr: 0 0 0 0 0 12 0 0 0 12 12 12 0 0 34 % T
% Val: 0 23 0 0 0 0 0 12 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 23 0 0 0 0 % W
% Tyr: 12 0 0 0 0 0 0 0 0 12 12 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _