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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGK223 All Species: 6.97
Human Site: S712 Identified Species: 19.17
UniProt: Q86YV5 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86YV5 NP_001074295 1406 149688 S712 R S G I E T F S P P P P P P K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094718 1322 141203 S706 P S S E L A H S P T N S G K K
Dog Lupus familis XP_540000 1393 147853 S682 R S G I E V F S P P P P P P K
Cat Felis silvestris
Mouse Mus musculus Q571I4 1179 126621 P595 G G G P A Q P P P L P Q K K I
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507039 1758 193149 R1047 I P K K I L S R I L H E A S V
Chicken Gallus gallus XP_420588 1313 142360 A705 S I R V S F T A G S S D S L D
Frog Xenopus laevis NP_001082542 1282 142382 S687 S L D S R T C S E E G H C F E
Zebra Danio Brachydanio rerio XP_001921602 1695 184654 S1008 P V Q E T E I S S A T S L P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001177956 680 74357 R96 S E D D D V T R S G G K R R A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 87.4 81.2 N.A. 66.4 N.A. N.A. 24.3 49.9 42.2 27.6 N.A. N.A. N.A. N.A. 21.3
Protein Similarity: 100 N.A. 89.4 85.6 N.A. 70.7 N.A. N.A. 38.5 60.3 55.3 41.1 N.A. N.A. N.A. N.A. 31.2
P-Site Identity: 100 N.A. 26.6 93.3 N.A. 20 N.A. N.A. 0 0 13.3 13.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 N.A. 26.6 93.3 N.A. 20 N.A. N.A. 0 13.3 20 13.3 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 12 12 0 12 0 12 0 0 12 0 23 % A
% Cys: 0 0 0 0 0 0 12 0 0 0 0 0 12 0 0 % C
% Asp: 0 0 23 12 12 0 0 0 0 0 0 12 0 0 12 % D
% Glu: 0 12 0 23 23 12 0 0 12 12 0 12 0 0 12 % E
% Phe: 0 0 0 0 0 12 23 0 0 0 0 0 0 12 0 % F
% Gly: 12 12 34 0 0 0 0 0 12 12 23 0 12 0 0 % G
% His: 0 0 0 0 0 0 12 0 0 0 12 12 0 0 0 % H
% Ile: 12 12 0 23 12 0 12 0 12 0 0 0 0 0 12 % I
% Lys: 0 0 12 12 0 0 0 0 0 0 0 12 12 23 34 % K
% Leu: 0 12 0 0 12 12 0 0 0 23 0 0 12 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % N
% Pro: 23 12 0 12 0 0 12 12 45 23 34 23 23 34 0 % P
% Gln: 0 0 12 0 0 12 0 0 0 0 0 12 0 0 0 % Q
% Arg: 23 0 12 0 12 0 0 23 0 0 0 0 12 12 0 % R
% Ser: 34 34 12 12 12 0 12 56 23 12 12 23 12 12 0 % S
% Thr: 0 0 0 0 12 23 23 0 0 12 12 0 0 0 0 % T
% Val: 0 12 0 12 0 23 0 0 0 0 0 0 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _