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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGK223 All Species: 5.76
Human Site: S860 Identified Species: 15.83
UniProt: Q86YV5 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86YV5 NP_001074295 1406 149688 S860 E T N V H D E S H F S Y S L S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094718 1322 141203 S854 L S V S S Q A S T G S T Q F Q
Dog Lupus familis XP_540000 1393 147853 E830 E S N V C A H E E S H F S Y S
Cat Felis silvestris
Mouse Mus musculus Q571I4 1179 126621 Y743 Y A K L G G L Y T Q S L A R L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507039 1758 193149 A1195 E N A L Y V V A N P T Y D I D
Chicken Gallus gallus XP_420588 1313 142360 T853 A T S K S T G T C V P S R N L
Frog Xenopus laevis NP_001082542 1282 142382 S835 S S S Q L S V S S Q N T S G S
Zebra Danio Brachydanio rerio XP_001921602 1695 184654 S1156 N P L Y D L E S T W D T A S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001177956 680 74357 V244 R T D A E G K V V P K R P V R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 87.4 81.2 N.A. 66.4 N.A. N.A. 24.3 49.9 42.2 27.6 N.A. N.A. N.A. N.A. 21.3
Protein Similarity: 100 N.A. 89.4 85.6 N.A. 70.7 N.A. N.A. 38.5 60.3 55.3 41.1 N.A. N.A. N.A. N.A. 31.2
P-Site Identity: 100 N.A. 13.3 33.3 N.A. 6.6 N.A. N.A. 13.3 6.6 20 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 N.A. 20 46.6 N.A. 20 N.A. N.A. 53.3 20 40 26.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 12 12 0 12 12 12 0 0 0 0 23 0 0 % A
% Cys: 0 0 0 0 12 0 0 0 12 0 0 0 0 0 0 % C
% Asp: 0 0 12 0 12 12 0 0 0 0 12 0 12 0 12 % D
% Glu: 34 0 0 0 12 0 23 12 12 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 12 0 12 0 12 0 % F
% Gly: 0 0 0 0 12 23 12 0 0 12 0 0 0 12 0 % G
% His: 0 0 0 0 12 0 12 0 12 0 12 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % I
% Lys: 0 0 12 12 0 0 12 0 0 0 12 0 0 0 0 % K
% Leu: 12 0 12 23 12 12 12 0 0 0 0 12 0 12 23 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 12 23 0 0 0 0 0 12 0 12 0 0 12 0 % N
% Pro: 0 12 0 0 0 0 0 0 0 23 12 0 12 0 0 % P
% Gln: 0 0 0 12 0 12 0 0 0 23 0 0 12 0 23 % Q
% Arg: 12 0 0 0 0 0 0 0 0 0 0 12 12 12 12 % R
% Ser: 12 34 23 12 23 12 0 45 12 12 34 12 34 12 34 % S
% Thr: 0 34 0 0 0 12 0 12 34 0 12 34 0 0 0 % T
% Val: 0 0 12 23 0 12 23 12 12 12 0 0 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % W
% Tyr: 12 0 0 12 12 0 0 12 0 0 0 23 0 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _