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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLB
All Species:
19.7
Human Site:
Y886
Identified Species:
39.39
UniProt:
Q86Z14
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Z14
NP_783864.1
1044
119808
Y886
N
Y
G
D
M
D
I
Y
I
T
A
S
G
I
D
Chimpanzee
Pan troglodytes
XP_526550
1044
119852
Y886
N
Y
G
D
M
D
I
Y
I
T
A
S
G
I
D
Rhesus Macaque
Macaca mulatta
XP_001091413
1044
119556
Y886
N
Y
G
D
M
D
I
Y
I
T
A
S
G
I
D
Dog
Lupus familis
XP_536257
1037
119179
Y886
N
Y
G
D
V
D
V
Y
I
T
A
S
G
I
D
Cat
Felis silvestris
Mouse
Mus musculus
Q99N32
1043
120170
Y884
N
Y
R
D
R
D
I
Y
I
T
A
N
G
I
D
Rat
Rattus norvegicus
Q9Z2Y9
1014
116781
V872
Y
G
D
L
P
M
F
V
T
A
N
G
I
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512722
1014
114479
D869
V
D
D
P
D
P
L
D
D
R
L
R
K
Y
Y
Chicken
Gallus gallus
XP_423224
607
70411
D471
D
D
Q
S
L
D
N
D
E
L
R
N
Y
Y
L
Frog
Xenopus laevis
NP_001106299
607
69234
Y471
D
G
V
D
L
R
G
Y
T
A
W
S
L
M
D
Zebra Danio
Brachydanio rerio
XP_690797
990
113270
E854
V
M
A
N
G
V
Q
E
D
T
A
R
F
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792744
548
62078
V412
K
E
Y
G
D
L
P
V
Y
V
T
E
N
G
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FZE0
510
58107
G374
T
V
T
L
P
F
K
G
L
S
T
I
G
D
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.1
85.5
N.A.
78.9
46.1
N.A.
67.9
41.7
25.1
42.1
N.A.
N.A.
N.A.
N.A.
25.1
Protein Similarity:
100
99.5
98.7
91.6
N.A.
88.8
62.7
N.A.
79.1
49.5
36.6
60.5
N.A.
N.A.
N.A.
N.A.
36.6
P-Site Identity:
100
100
100
86.6
N.A.
80
6.6
N.A.
0
6.6
26.6
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
6.6
N.A.
6.6
26.6
46.6
26.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
0
17
50
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
17
17
50
17
50
0
17
17
0
0
0
0
17
67
% D
% Glu:
0
9
0
0
0
0
0
9
9
0
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
9
9
0
0
0
0
0
9
0
0
% F
% Gly:
0
17
34
9
9
0
9
9
0
0
0
9
50
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
34
0
42
0
0
9
9
42
0
% I
% Lys:
9
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% K
% Leu:
0
0
0
17
17
9
9
0
9
9
9
0
9
0
9
% L
% Met:
0
9
0
0
25
9
0
0
0
0
0
0
0
9
0
% M
% Asn:
42
0
0
9
0
0
9
0
0
0
9
17
9
0
0
% N
% Pro:
0
0
0
9
17
9
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
9
9
0
0
0
9
9
17
0
9
9
% R
% Ser:
0
0
0
9
0
0
0
0
0
9
0
42
0
0
0
% S
% Thr:
9
0
9
0
0
0
0
0
17
50
17
0
0
0
0
% T
% Val:
17
9
9
0
9
9
9
17
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
9
42
9
0
0
0
0
50
9
0
0
0
9
17
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _