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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLB
All Species:
21.82
Human Site:
Y910
Identified Species:
43.64
UniProt:
Q86Z14
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Z14
NP_783864.1
1044
119808
Y910
R
K
Y
Y
L
G
K
Y
L
Q
E
V
L
K
A
Chimpanzee
Pan troglodytes
XP_526550
1044
119852
Y910
R
K
Y
Y
L
G
K
Y
L
Q
E
V
L
K
A
Rhesus Macaque
Macaca mulatta
XP_001091413
1044
119556
Y910
R
K
Y
Y
L
E
K
Y
L
Q
E
V
L
K
A
Dog
Lupus familis
XP_536257
1037
119179
Y910
R
K
Y
Y
L
E
K
Y
I
Q
E
A
L
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q99N32
1043
120170
Y908
R
K
Y
Y
L
E
K
Y
V
Q
E
A
L
K
A
Rat
Rattus norvegicus
Q9Z2Y9
1014
116781
Y896
R
M
Y
Y
I
K
N
Y
V
N
E
A
L
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512722
1014
114479
I893
K
A
S
Q
I
D
K
I
N
V
K
G
Y
Y
A
Chicken
Gallus gallus
XP_423224
607
70411
K495
A
Y
Y
V
D
K
V
K
V
R
G
Y
Y
A
F
Frog
Xenopus laevis
NP_001106299
607
69234
T495
E
R
F
G
L
H
Y
T
N
Y
S
D
P
E
L
Zebra Danio
Brachydanio rerio
XP_690797
990
113270
A878
Y
V
N
E
A
L
K
A
Y
M
L
D
A
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792744
548
62078
Y436
D
V
M
R
Q
K
Y
Y
T
S
Y
I
N
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FZE0
510
58107
M398
P
R
G
M
R
S
L
M
N
Y
I
K
H
R
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.1
85.5
N.A.
78.9
46.1
N.A.
67.9
41.7
25.1
42.1
N.A.
N.A.
N.A.
N.A.
25.1
Protein Similarity:
100
99.5
98.7
91.6
N.A.
88.8
62.7
N.A.
79.1
49.5
36.6
60.5
N.A.
N.A.
N.A.
N.A.
36.6
P-Site Identity:
100
100
93.3
80
N.A.
80
53.3
N.A.
13.3
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
66.6
N.A.
33.3
20
26.6
6.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
9
0
0
9
0
0
0
25
9
9
59
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
9
9
0
0
0
0
0
17
0
0
0
% D
% Glu:
9
0
0
9
0
25
0
0
0
0
50
0
0
17
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
9
9
0
17
0
0
0
0
9
9
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
17
0
0
9
9
0
9
9
0
0
0
% I
% Lys:
9
42
0
0
0
25
59
9
0
0
9
9
0
50
0
% K
% Leu:
0
0
0
0
50
9
9
0
25
0
9
0
50
0
9
% L
% Met:
0
9
9
9
0
0
0
9
0
9
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
9
0
25
9
0
0
9
0
9
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
9
9
0
0
0
0
42
0
0
0
0
0
% Q
% Arg:
50
17
0
9
9
0
0
0
0
9
0
0
0
9
0
% R
% Ser:
0
0
9
0
0
9
0
0
0
9
9
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% T
% Val:
0
17
0
9
0
0
9
0
25
9
0
25
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
59
50
0
0
17
59
9
17
9
9
17
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _