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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLB
All Species:
16.67
Human Site:
Y918
Identified Species:
33.33
UniProt:
Q86Z14
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Z14
NP_783864.1
1044
119808
Y918
L
Q
E
V
L
K
A
Y
L
I
D
K
V
R
I
Chimpanzee
Pan troglodytes
XP_526550
1044
119852
Y918
L
Q
E
V
L
K
A
Y
L
I
D
K
V
R
I
Rhesus Macaque
Macaca mulatta
XP_001091413
1044
119556
Y918
L
Q
E
V
L
K
A
Y
L
I
D
K
V
R
I
Dog
Lupus familis
XP_536257
1037
119179
H918
I
Q
E
A
L
K
A
H
L
I
D
K
V
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q99N32
1043
120170
Y916
V
Q
E
A
L
K
A
Y
L
I
D
K
V
K
I
Rat
Rattus norvegicus
Q9Z2Y9
1014
116781
Y904
V
N
E
A
L
K
A
Y
V
L
D
G
I
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512722
1014
114479
F901
N
V
K
G
Y
Y
A
F
K
L
T
E
E
K
S
Chicken
Gallus gallus
XP_423224
607
70411
K503
V
R
G
Y
Y
A
F
K
L
T
E
E
K
S
K
Frog
Xenopus laevis
NP_001106299
607
69234
A503
N
Y
S
D
P
E
L
A
R
I
P
K
K
S
T
Zebra Danio
Brachydanio rerio
XP_690797
990
113270
L886
Y
M
L
D
A
V
N
L
K
G
Y
F
A
Y
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792744
548
62078
L444
T
S
Y
I
N
E
V
L
K
A
I
E
V
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FZE0
510
58107
G406
N
Y
I
K
H
R
Y
G
N
P
P
V
F
I
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.1
85.5
N.A.
78.9
46.1
N.A.
67.9
41.7
25.1
42.1
N.A.
N.A.
N.A.
N.A.
25.1
Protein Similarity:
100
99.5
98.7
91.6
N.A.
88.8
62.7
N.A.
79.1
49.5
36.6
60.5
N.A.
N.A.
N.A.
N.A.
36.6
P-Site Identity:
100
100
100
66.6
N.A.
80
40
N.A.
6.6
6.6
13.3
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
73.3
N.A.
40
33.3
20
0
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
25
9
9
59
9
0
9
0
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
17
0
0
0
0
0
0
50
0
0
9
0
% D
% Glu:
0
0
50
0
0
17
0
0
0
0
9
25
9
0
9
% E
% Phe:
0
0
0
0
0
0
9
9
0
0
0
9
9
0
0
% F
% Gly:
0
0
9
9
0
0
0
9
0
9
0
9
0
0
0
% G
% His:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
9
0
9
9
0
0
0
0
0
50
9
0
9
9
34
% I
% Lys:
0
0
9
9
0
50
0
9
25
0
0
50
17
25
9
% K
% Leu:
25
0
9
0
50
0
9
17
50
17
0
0
0
0
9
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
25
9
0
0
9
0
9
0
9
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
9
17
0
0
0
0
% P
% Gln:
0
42
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
9
0
0
9
0
0
0
0
25
0
% R
% Ser:
0
9
9
0
0
0
0
0
0
0
0
0
0
17
9
% S
% Thr:
9
0
0
0
0
0
0
0
0
9
9
0
0
0
17
% T
% Val:
25
9
0
25
0
9
9
0
9
0
0
9
50
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
17
9
9
17
9
9
42
0
0
9
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _