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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC125 All Species: 16.97
Human Site: S387 Identified Species: 41.48
UniProt: Q86Z20 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86Z20 NP_789786.2 511 58629 S387 R L L G M L P S E N S S K R M
Chimpanzee Pan troglodytes P61584 1003 117506 N520 K E E I E E K N R E N L K K I
Rhesus Macaque Macaca mulatta XP_001092742 277 31349 M172 S P Q E V L K M L I D L L N D
Dog Lupus familis XP_544367 510 57675 S386 K L L G M L P S E N S S K K V
Cat Felis silvestris
Mouse Mus musculus Q5U465 500 56593 S375 R L L G I L P S E N S S K G A
Rat Rattus norvegicus NP_001128233 508 57304 L382 R L L G I L P L E N S S K S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512347 540 61498 S384 K L R G M L I S G S D C R K M
Chicken Gallus gallus XP_424893 508 56771 S373 K L S G L L S S D A D S R K V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2BGP7 465 53808 S353 T S D G R I P S D S S E T L H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798286 493 55563 R387 D G E K N G M R R R P L Q L P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20.1 50.8 74.7 N.A. 71.8 70.4 N.A. 52.5 52.2 N.A. 38.9 N.A. N.A. N.A. N.A. 26.2
Protein Similarity: 100 32.2 52.2 86.3 N.A. 82.3 82.5 N.A. 65.9 67.7 N.A. 54.9 N.A. N.A. N.A. N.A. 45.6
P-Site Identity: 100 6.6 6.6 80 N.A. 80 73.3 N.A. 40 33.3 N.A. 26.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 40 13.3 100 N.A. 86.6 80 N.A. 66.6 73.3 N.A. 46.6 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 10 0 10 0 0 0 0 0 20 0 30 0 0 0 10 % D
% Glu: 0 10 20 10 10 10 0 0 40 10 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 70 0 10 0 0 10 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 10 20 10 10 0 0 10 0 0 0 0 10 % I
% Lys: 40 0 0 10 0 0 20 0 0 0 0 0 50 40 0 % K
% Leu: 0 60 40 0 10 70 0 10 10 0 0 30 10 20 0 % L
% Met: 0 0 0 0 30 0 10 10 0 0 0 0 0 0 20 % M
% Asn: 0 0 0 0 10 0 0 10 0 40 10 0 0 10 0 % N
% Pro: 0 10 0 0 0 0 50 0 0 0 10 0 0 0 10 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 30 0 10 0 10 0 0 10 20 10 0 0 20 10 0 % R
% Ser: 10 10 10 0 0 0 10 60 0 20 50 50 0 10 0 % S
% Thr: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % T
% Val: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _