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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC125
All Species:
16.97
Human Site:
S387
Identified Species:
41.48
UniProt:
Q86Z20
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Z20
NP_789786.2
511
58629
S387
R
L
L
G
M
L
P
S
E
N
S
S
K
R
M
Chimpanzee
Pan troglodytes
P61584
1003
117506
N520
K
E
E
I
E
E
K
N
R
E
N
L
K
K
I
Rhesus Macaque
Macaca mulatta
XP_001092742
277
31349
M172
S
P
Q
E
V
L
K
M
L
I
D
L
L
N
D
Dog
Lupus familis
XP_544367
510
57675
S386
K
L
L
G
M
L
P
S
E
N
S
S
K
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q5U465
500
56593
S375
R
L
L
G
I
L
P
S
E
N
S
S
K
G
A
Rat
Rattus norvegicus
NP_001128233
508
57304
L382
R
L
L
G
I
L
P
L
E
N
S
S
K
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512347
540
61498
S384
K
L
R
G
M
L
I
S
G
S
D
C
R
K
M
Chicken
Gallus gallus
XP_424893
508
56771
S373
K
L
S
G
L
L
S
S
D
A
D
S
R
K
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2BGP7
465
53808
S353
T
S
D
G
R
I
P
S
D
S
S
E
T
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798286
493
55563
R387
D
G
E
K
N
G
M
R
R
R
P
L
Q
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.1
50.8
74.7
N.A.
71.8
70.4
N.A.
52.5
52.2
N.A.
38.9
N.A.
N.A.
N.A.
N.A.
26.2
Protein Similarity:
100
32.2
52.2
86.3
N.A.
82.3
82.5
N.A.
65.9
67.7
N.A.
54.9
N.A.
N.A.
N.A.
N.A.
45.6
P-Site Identity:
100
6.6
6.6
80
N.A.
80
73.3
N.A.
40
33.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
40
13.3
100
N.A.
86.6
80
N.A.
66.6
73.3
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
10
0
10
0
0
0
0
0
20
0
30
0
0
0
10
% D
% Glu:
0
10
20
10
10
10
0
0
40
10
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
70
0
10
0
0
10
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
10
20
10
10
0
0
10
0
0
0
0
10
% I
% Lys:
40
0
0
10
0
0
20
0
0
0
0
0
50
40
0
% K
% Leu:
0
60
40
0
10
70
0
10
10
0
0
30
10
20
0
% L
% Met:
0
0
0
0
30
0
10
10
0
0
0
0
0
0
20
% M
% Asn:
0
0
0
0
10
0
0
10
0
40
10
0
0
10
0
% N
% Pro:
0
10
0
0
0
0
50
0
0
0
10
0
0
0
10
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
30
0
10
0
10
0
0
10
20
10
0
0
20
10
0
% R
% Ser:
10
10
10
0
0
0
10
60
0
20
50
50
0
10
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _