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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC125 All Species: 0.91
Human Site: T24 Identified Species: 2.22
UniProt: Q86Z20 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86Z20 NP_789786.2 511 58629 T24 E T E E D D M T E G D L G Y G
Chimpanzee Pan troglodytes P61584 1003 117506 S76 A D K S L Q E S L Q K T I Y K
Rhesus Macaque Macaca mulatta XP_001092742 277 31349
Dog Lupus familis XP_544367 510 57675 D24 E T E D D L A D G D L G Y G L
Cat Felis silvestris
Mouse Mus musculus Q5U465 500 56593 D25 E D D M T E G D L G Y G L G R
Rat Rattus norvegicus NP_001128233 508 57304 G24 A E D D M T E G D L G Y G L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512347 540 61498 E24 R R P G G L Y E M G S L S V C
Chicken Gallus gallus XP_424893 508 56771 E27 R R P G G V Y E G E K L Q N Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2BGP7 465 53808 L25 R G R F L D F L S H S R P I K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798286 493 55563 R50 G A E L G V R R S Q H G G S T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20.1 50.8 74.7 N.A. 71.8 70.4 N.A. 52.5 52.2 N.A. 38.9 N.A. N.A. N.A. N.A. 26.2
Protein Similarity: 100 32.2 52.2 86.3 N.A. 82.3 82.5 N.A. 65.9 67.7 N.A. 54.9 N.A. N.A. N.A. N.A. 45.6
P-Site Identity: 100 6.6 0 26.6 N.A. 13.3 6.6 N.A. 13.3 6.6 N.A. 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 20 0 33.3 N.A. 26.6 26.6 N.A. 13.3 6.6 N.A. 6.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 20 20 20 20 20 0 20 10 10 10 0 0 0 0 % D
% Glu: 30 10 30 10 0 10 20 20 10 10 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 0 20 30 0 10 10 20 30 10 30 30 20 10 % G
% His: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 20 0 0 0 20 % K
% Leu: 0 0 0 10 20 20 0 10 20 10 10 30 10 10 10 % L
% Met: 0 0 0 10 10 0 10 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 20 0 0 0 0 0 0 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 20 0 0 10 0 0 % Q
% Arg: 30 20 10 0 0 0 10 10 0 0 0 10 0 0 20 % R
% Ser: 0 0 0 10 0 0 0 10 20 0 20 0 10 10 0 % S
% Thr: 0 20 0 0 10 10 0 10 0 0 0 10 0 0 10 % T
% Val: 0 0 0 0 0 20 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 20 0 0 0 10 10 10 20 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _