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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC125
All Species:
3.94
Human Site:
T498
Identified Species:
9.63
UniProt:
Q86Z20
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Z20
NP_789786.2
511
58629
T498
Q
I
D
P
N
Y
R
T
L
K
R
S
H
S
L
Chimpanzee
Pan troglodytes
P61584
1003
117506
I847
E
I
P
K
I
F
Q
I
L
Y
A
N
E
G
E
Rhesus Macaque
Macaca mulatta
XP_001092742
277
31349
L265
I
D
P
N
Y
R
T
L
K
R
S
H
S
L
P
Dog
Lupus familis
XP_544367
510
57675
R496
H
R
V
Q
N
C
T
R
T
L
K
R
S
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5U465
500
56593
T486
K
V
S
D
C
P
R
T
L
K
R
S
C
S
L
Rat
Rattus norvegicus
NP_001128233
508
57304
R490
R
K
V
S
G
C
S
R
A
L
K
R
S
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512347
540
61498
R495
E
I
P
Q
S
T
S
R
T
L
K
K
S
H
S
Chicken
Gallus gallus
XP_424893
508
56771
V477
G
F
Q
N
S
V
R
V
L
Q
K
S
H
S
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2BGP7
465
53808
S452
Y
K
A
N
Q
P
P
S
E
N
R
P
E
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798286
493
55563
Q481
K
M
L
A
R
R
T
Q
D
L
E
A
T
M
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.1
50.8
74.7
N.A.
71.8
70.4
N.A.
52.5
52.2
N.A.
38.9
N.A.
N.A.
N.A.
N.A.
26.2
Protein Similarity:
100
32.2
52.2
86.3
N.A.
82.3
82.5
N.A.
65.9
67.7
N.A.
54.9
N.A.
N.A.
N.A.
N.A.
45.6
P-Site Identity:
100
13.3
0
6.6
N.A.
53.3
0
N.A.
6.6
33.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
40
6.6
13.3
N.A.
66.6
13.3
N.A.
26.6
53.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
0
0
10
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
10
20
0
0
0
0
0
0
10
20
0
% C
% Asp:
0
10
10
10
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
20
0
0
0
0
0
0
0
10
0
10
0
20
0
10
% E
% Phe:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
10
20
10
0
% H
% Ile:
10
30
0
0
10
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
20
20
0
10
0
0
0
0
10
20
40
10
0
0
20
% K
% Leu:
0
0
10
0
0
0
0
10
40
40
0
0
0
10
20
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
30
20
0
0
0
0
10
0
10
0
0
0
% N
% Pro:
0
0
30
10
0
20
10
0
0
0
0
10
0
0
10
% P
% Gln:
10
0
10
20
10
0
10
10
0
10
0
0
0
0
0
% Q
% Arg:
10
10
0
0
10
20
30
30
0
10
30
20
0
0
0
% R
% Ser:
0
0
10
10
20
0
20
10
0
0
10
30
40
30
30
% S
% Thr:
0
0
0
0
0
10
30
20
20
0
0
0
10
10
0
% T
% Val:
0
10
20
0
0
10
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
10
0
0
0
10
10
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _