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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFX6
All Species:
15.45
Human Site:
S605
Identified Species:
42.5
UniProt:
Q8HWS3
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8HWS3
NP_775831.1
928
102461
S605
T
Y
L
P
L
P
S
S
Q
P
G
G
L
G
P
Chimpanzee
Pan troglodytes
XP_527584
928
102435
S605
A
Y
L
P
L
P
S
S
Q
S
G
G
L
G
P
Rhesus Macaque
Macaca mulatta
XP_001110999
928
102511
S605
T
Y
L
P
L
P
S
S
Q
S
G
G
L
G
P
Dog
Lupus familis
XP_541213
922
101460
S599
T
Y
L
P
L
S
S
S
H
P
G
G
L
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C7R7
927
102547
S604
S
Y
V
P
L
P
S
S
Q
P
G
A
I
P
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520466
405
45149
N84
H
L
L
P
L
L
E
N
P
I
I
V
D
I
F
Chicken
Gallus gallus
XP_419769
1002
110540
A679
Q
T
Y
V
S
L
S
A
S
Q
P
S
S
M
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5RJA1
848
93744
D528
K
D
E
I
P
P
E
D
D
Y
L
T
L
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790469
942
105870
N575
E
V
I
D
H
N
R
N
T
L
Y
P
G
H
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.3
90.8
N.A.
87.3
N.A.
N.A.
37.9
72.7
N.A.
63.2
N.A.
N.A.
N.A.
N.A.
46.5
Protein Similarity:
100
99.4
98.8
93.8
N.A.
91.6
N.A.
N.A.
40.8
79.6
N.A.
73.4
N.A.
N.A.
N.A.
N.A.
60.5
P-Site Identity:
100
86.6
93.3
73.3
N.A.
66.6
N.A.
N.A.
20
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
86.6
93.3
73.3
N.A.
86.6
N.A.
N.A.
26.6
20
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
12
0
0
0
12
0
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
12
0
0
0
12
12
0
0
0
12
0
0
% D
% Glu:
12
0
12
0
0
0
23
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
56
45
12
34
0
% G
% His:
12
0
0
0
12
0
0
0
12
0
0
0
0
12
0
% H
% Ile:
0
0
12
12
0
0
0
0
0
12
12
0
12
12
0
% I
% Lys:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
56
0
67
23
0
0
0
12
12
0
56
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
12
% M
% Asn:
0
0
0
0
0
12
0
23
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
67
12
56
0
0
12
34
12
12
0
23
56
% P
% Gln:
12
0
0
0
0
0
0
0
45
12
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
0
0
12
12
67
56
12
23
0
12
12
0
12
% S
% Thr:
34
12
0
0
0
0
0
0
12
0
0
12
0
0
0
% T
% Val:
0
12
12
12
0
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
56
12
0
0
0
0
0
0
12
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _