KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCP2
All Species:
32.73
Human Site:
S246
Identified Species:
55.38
UniProt:
Q8IU60
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IU60
NP_689837.2
420
48457
S246
L
S
R
R
F
G
D
S
S
D
S
D
N
G
F
Chimpanzee
Pan troglodytes
XP_001147135
420
48432
S246
L
S
R
R
F
G
D
S
S
D
S
D
N
G
F
Rhesus Macaque
Macaca mulatta
XP_001082528
420
48390
S246
L
S
R
R
F
G
D
S
S
D
S
D
N
G
F
Dog
Lupus familis
XP_546202
645
72130
S469
L
S
R
R
F
G
D
S
S
D
S
D
N
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYC6
422
48378
S246
L
S
R
R
F
G
D
S
S
D
S
D
N
G
F
Rat
Rattus norvegicus
XP_225963
494
56278
S319
L
S
R
R
F
G
D
S
S
D
S
D
N
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507135
414
48079
S238
L
S
R
R
F
G
D
S
S
D
S
D
N
G
F
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089058
419
48143
S246
L
H
R
K
F
G
D
S
S
D
S
D
N
G
F
Zebra Danio
Brachydanio rerio
NP_956446
397
45524
A240
R
Q
L
K
E
W
I
A
K
H
K
G
E
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648805
791
87472
T519
N
N
L
N
G
K
G
T
V
G
T
G
A
G
S
Honey Bee
Apis mellifera
XP_395977
232
27158
A80
P
F
L
K
P
H
V
A
N
I
D
N
I
L
E
Nematode Worm
Caenorhab. elegans
O62255
786
87350
F408
S
S
I
F
S
Q
L
F
P
A
Q
P
P
P
P
Sea Urchin
Strong. purpuratus
XP_786436
233
27225
A80
C
P
F
L
I
D
H
A
D
K
V
D
K
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53550
970
108649
K477
G
T
D
L
N
S
I
K
Q
N
N
N
D
E
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99
62.9
N.A.
91.9
78.9
N.A.
81.6
N.A.
70.9
67.6
N.A.
25
32.6
23.2
31.4
Protein Similarity:
100
99.7
99.5
64.1
N.A.
95.2
81.3
N.A.
89.5
N.A.
83.5
78.8
N.A.
34.1
42.3
33.4
43.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
N.A.
86.6
0
N.A.
6.6
0
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
N.A.
93.3
13.3
N.A.
26.6
26.6
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
28.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
22
0
8
0
0
8
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
58
0
8
58
8
65
8
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
0
0
8
8
8
% E
% Phe:
0
8
8
8
58
0
0
8
0
0
0
0
0
0
58
% F
% Gly:
8
0
0
0
8
58
8
0
0
8
0
15
0
65
0
% G
% His:
0
8
0
0
0
8
8
0
0
8
0
0
0
0
8
% H
% Ile:
0
0
8
0
8
0
15
0
0
8
0
0
8
0
0
% I
% Lys:
0
0
0
22
0
8
0
8
8
8
8
0
8
0
0
% K
% Leu:
58
0
22
15
0
0
8
0
0
0
0
0
0
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
8
8
0
0
0
8
8
8
15
58
0
0
% N
% Pro:
8
8
0
0
8
0
0
0
8
0
0
8
8
8
8
% P
% Gln:
0
8
0
0
0
8
0
0
8
0
8
0
0
0
0
% Q
% Arg:
8
0
58
50
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
58
0
0
8
8
0
58
58
0
58
0
0
8
8
% S
% Thr:
0
8
0
0
0
0
0
8
0
0
8
0
0
0
15
% T
% Val:
0
0
0
0
0
0
8
0
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _