KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCP2
All Species:
31.21
Human Site:
T259
Identified Species:
52.82
UniProt:
Q8IU60
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IU60
NP_689837.2
420
48457
T259
G
F
S
S
T
G
S
T
P
A
K
P
T
V
E
Chimpanzee
Pan troglodytes
XP_001147135
420
48432
T259
G
F
S
S
T
G
S
T
P
A
K
P
T
V
E
Rhesus Macaque
Macaca mulatta
XP_001082528
420
48390
T259
G
F
S
S
T
G
S
T
P
A
K
P
T
V
E
Dog
Lupus familis
XP_546202
645
72130
T482
G
F
S
S
V
G
S
T
P
A
K
P
T
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYC6
422
48378
T259
G
F
S
S
A
G
S
T
P
A
R
P
T
V
E
Rat
Rattus norvegicus
XP_225963
494
56278
T332
G
F
S
S
A
G
S
T
P
A
R
P
T
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507135
414
48079
T251
G
F
C
S
A
G
S
T
P
V
R
P
S
V
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089058
419
48143
T259
G
F
A
S
A
G
S
T
P
S
K
P
N
A
E
Zebra Danio
Brachydanio rerio
NP_956446
397
45524
F253
S
T
S
S
D
E
D
F
A
S
N
G
S
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648805
791
87472
A532
G
S
A
A
S
A
S
A
T
A
A
I
N
S
M
Honey Bee
Apis mellifera
XP_395977
232
27158
K93
L
E
Q
W
R
D
Y
K
Q
N
V
P
T
F
G
Nematode Worm
Caenorhab. elegans
O62255
786
87350
T421
P
P
V
P
E
D
A
T
P
T
R
P
M
Y
K
Sea Urchin
Strong. purpuratus
XP_786436
233
27225
Y93
L
H
A
E
W
R
E
Y
K
M
S
V
P
T
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53550
970
108649
Q490
E
T
A
H
S
N
S
Q
A
L
L
D
L
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99
62.9
N.A.
91.9
78.9
N.A.
81.6
N.A.
70.9
67.6
N.A.
25
32.6
23.2
31.4
Protein Similarity:
100
99.7
99.5
64.1
N.A.
95.2
81.3
N.A.
89.5
N.A.
83.5
78.8
N.A.
34.1
42.3
33.4
43.5
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
66.6
N.A.
66.6
13.3
N.A.
20
13.3
20
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
80
N.A.
80
26.6
N.A.
40
13.3
40
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
28.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
29
8
29
8
8
8
15
50
8
0
0
8
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
15
8
0
0
0
0
8
0
0
0
% D
% Glu:
8
8
0
8
8
8
8
0
0
0
0
0
0
0
58
% E
% Phe:
0
58
0
0
0
0
0
8
0
0
0
0
0
8
0
% F
% Gly:
65
0
0
0
0
58
0
0
0
0
0
8
0
0
8
% G
% His:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
8
0
36
0
0
0
15
% K
% Leu:
15
0
0
0
0
0
0
0
0
8
8
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
8
% M
% Asn:
0
0
0
0
0
8
0
0
0
8
8
0
15
0
0
% N
% Pro:
8
8
0
8
0
0
0
0
65
0
0
72
8
0
8
% P
% Gln:
0
0
8
0
0
0
0
8
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
8
0
0
0
0
29
0
0
0
0
% R
% Ser:
8
8
50
65
15
0
72
0
0
15
8
0
15
8
0
% S
% Thr:
0
15
0
0
22
0
0
65
8
8
0
0
50
15
0
% T
% Val:
0
0
8
0
8
0
0
0
0
8
8
8
0
50
0
% V
% Trp:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
8
0
0
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _