KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRF2BP1
All Species:
8.48
Human Site:
S118
Identified Species:
20.74
UniProt:
Q8IU81
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IU81
NP_056464.1
584
61688
S118
R
Y
D
R
A
T
S
S
G
R
L
P
L
P
S
Chimpanzee
Pan troglodytes
Q5YCW1
776
80960
K189
R
H
A
P
E
L
L
K
H
Q
L
L
G
D
L
Rhesus Macaque
Macaca mulatta
Q2MJS2
794
82427
A219
Q
S
P
N
S
S
S
A
A
A
S
V
A
S
R
Dog
Lupus familis
XP_541548
584
61625
S118
R
Y
D
R
A
T
S
S
G
R
L
P
L
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3Y8
584
61732
S118
R
Y
D
R
A
T
S
S
S
R
L
A
L
P
S
Rat
Rattus norvegicus
Q5EIC4
783
81477
F159
A
V
E
Q
R
S
R
F
E
Y
P
P
P
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519945
226
23147
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PCG7
690
72830
R115
S
A
A
S
G
L
E
R
Y
G
L
A
T
E
R
Zebra Danio
Brachydanio rerio
Q1LV17
605
64887
P121
R
L
E
D
G
G
P
P
E
V
S
R
Q
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784488
661
71839
A133
V
T
H
E
P
S
R
A
R
S
I
H
D
F
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.4
44.4
98.8
N.A.
96.4
45.2
N.A.
27.7
N.A.
46.9
52.5
N.A.
N.A.
N.A.
N.A.
37.9
Protein Similarity:
100
31.8
54
99.3
N.A.
97.2
54.7
N.A.
32.5
N.A.
58.7
65.7
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
13.3
6.6
100
N.A.
86.6
13.3
N.A.
0
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
33.3
100
N.A.
86.6
33.3
N.A.
0
N.A.
6.6
13.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
20
0
30
0
0
20
10
10
0
20
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
30
10
0
0
0
0
0
0
0
0
10
10
0
% D
% Glu:
0
0
20
10
10
0
10
0
20
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
20
10
0
0
20
10
0
0
10
0
0
% G
% His:
0
10
10
0
0
0
0
0
10
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
20
10
0
0
0
50
10
30
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
10
10
0
10
10
0
0
10
30
10
40
10
% P
% Gln:
10
0
0
10
0
0
0
0
0
10
0
0
10
0
0
% Q
% Arg:
50
0
0
30
10
0
20
10
10
30
0
10
0
0
20
% R
% Ser:
10
10
0
10
10
30
40
30
10
10
20
0
0
20
40
% S
% Thr:
0
10
0
0
0
30
0
0
0
0
0
0
10
0
0
% T
% Val:
10
10
0
0
0
0
0
0
0
10
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
30
0
0
0
0
0
0
10
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _