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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRF2BP1
All Species:
10.3
Human Site:
S125
Identified Species:
25.19
UniProt:
Q8IU81
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IU81
NP_056464.1
584
61688
S125
S
G
R
L
P
L
P
S
P
A
L
E
Y
T
L
Chimpanzee
Pan troglodytes
Q5YCW1
776
80960
L196
K
H
Q
L
L
G
D
L
H
Q
E
G
P
P
L
Rhesus Macaque
Macaca mulatta
Q2MJS2
794
82427
R226
A
A
A
S
V
A
S
R
R
G
T
H
G
G
L
Dog
Lupus familis
XP_541548
584
61625
S125
S
G
R
L
P
L
P
S
P
A
L
E
Y
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3Y8
584
61732
S125
S
S
R
L
A
L
P
S
P
A
L
E
Y
T
L
Rat
Rattus norvegicus
Q5EIC4
783
81477
V166
F
E
Y
P
P
P
P
V
S
L
G
S
S
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519945
226
23147
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PCG7
690
72830
R122
R
Y
G
L
A
T
E
R
G
R
F
E
Y
S
L
Zebra Danio
Brachydanio rerio
Q1LV17
605
64887
P128
P
E
V
S
R
Q
S
P
T
A
R
R
T
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784488
661
71839
S140
A
R
S
I
H
D
F
S
T
A
Q
K
F
G
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.4
44.4
98.8
N.A.
96.4
45.2
N.A.
27.7
N.A.
46.9
52.5
N.A.
N.A.
N.A.
N.A.
37.9
Protein Similarity:
100
31.8
54
99.3
N.A.
97.2
54.7
N.A.
32.5
N.A.
58.7
65.7
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
13.3
6.6
100
N.A.
86.6
13.3
N.A.
0
N.A.
26.6
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
20
13.3
100
N.A.
86.6
20
N.A.
0
N.A.
33.3
13.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
10
10
0
20
10
0
0
0
50
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
20
0
0
0
0
10
0
0
0
10
40
0
0
0
% E
% Phe:
10
0
0
0
0
0
10
0
0
0
10
0
10
0
0
% F
% Gly:
0
20
10
0
0
10
0
0
10
10
10
10
10
20
0
% G
% His:
0
10
0
0
10
0
0
0
10
0
0
10
0
0
10
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
0
50
10
30
0
10
0
10
30
0
0
10
60
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
10
30
10
40
10
30
0
0
0
10
10
0
% P
% Gln:
0
0
10
0
0
10
0
0
0
10
10
0
0
0
0
% Q
% Arg:
10
10
30
0
10
0
0
20
10
10
10
10
0
0
0
% R
% Ser:
30
10
10
20
0
0
20
40
10
0
0
10
10
20
0
% S
% Thr:
0
0
0
0
0
10
0
0
20
0
10
0
10
30
0
% T
% Val:
0
0
10
0
10
0
0
10
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
0
0
0
0
0
0
0
0
0
40
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _