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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRF2BP1
All Species:
16.97
Human Site:
S194
Identified Species:
41.48
UniProt:
Q8IU81
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IU81
NP_056464.1
584
61688
S194
P
A
R
P
L
F
G
S
D
F
E
K
E
K
Q
Chimpanzee
Pan troglodytes
Q5YCW1
776
80960
A264
P
G
F
P
A
E
G
A
I
P
L
P
V
D
F
Rhesus Macaque
Macaca mulatta
Q2MJS2
794
82427
T336
R
P
G
S
V
S
S
T
D
Q
E
R
E
L
K
Dog
Lupus familis
XP_541548
584
61625
S194
P
A
R
P
A
F
G
S
D
F
E
K
E
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3Y8
584
61732
S194
P
A
R
P
L
F
G
S
D
F
E
K
E
K
Q
Rat
Rattus norvegicus
Q5EIC4
783
81477
T325
R
P
G
S
V
S
S
T
D
Q
E
R
E
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519945
226
23147
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PCG7
690
72830
S231
P
K
R
P
G
S
V
S
S
T
D
Q
E
R
E
Zebra Danio
Brachydanio rerio
Q1LV17
605
64887
A198
V
G
V
P
S
F
M
A
P
E
F
E
K
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784488
661
71839
S215
P
P
T
T
T
P
G
S
G
G
T
K
R
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.4
44.4
98.8
N.A.
96.4
45.2
N.A.
27.7
N.A.
46.9
52.5
N.A.
N.A.
N.A.
N.A.
37.9
Protein Similarity:
100
31.8
54
99.3
N.A.
97.2
54.7
N.A.
32.5
N.A.
58.7
65.7
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
20
20
93.3
N.A.
100
20
N.A.
0
N.A.
33.3
13.3
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
26.6
46.6
93.3
N.A.
100
46.6
N.A.
0
N.A.
60
40
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
30
0
0
20
0
0
20
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
50
0
10
0
0
10
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
10
50
10
60
10
10
% E
% Phe:
0
0
10
0
0
40
0
0
0
30
10
0
0
0
20
% F
% Gly:
0
20
20
0
10
0
50
0
10
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
40
10
30
20
% K
% Leu:
0
0
0
0
20
0
0
0
0
0
10
0
0
20
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
60
30
0
60
0
10
0
0
10
10
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
20
0
10
0
0
30
% Q
% Arg:
20
0
40
0
0
0
0
0
0
0
0
20
10
10
0
% R
% Ser:
0
0
0
20
10
30
20
50
10
0
0
0
0
10
0
% S
% Thr:
0
0
10
10
10
0
0
20
0
10
10
0
0
0
0
% T
% Val:
10
0
10
0
20
0
10
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _