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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IRF2BP1 All Species: 18.48
Human Site: S237 Identified Species: 45.19
UniProt: Q8IU81 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IU81 NP_056464.1 584 61688 S237 R E Q L L A L S A C A P F N V
Chimpanzee Pan troglodytes Q5YCW1 776 80960 Q315 T P N V Q K E Q A H S E E H L
Rhesus Macaque Macaca mulatta Q2MJS2 794 82427 A381 R D T L L T L A G C T P Y E V
Dog Lupus familis XP_541548 584 61625 S237 R E Q L L A L S A C A P F N V
Cat Felis silvestris
Mouse Mus musculus Q8R3Y8 584 61732 S237 R E Q L L A L S A C A P F N V
Rat Rattus norvegicus Q5EIC4 783 81477 A370 R D T L L T L A G C T P Y E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519945 226 23147
Chicken Gallus gallus
Frog Xenopus laevis Q6PCG7 690 72830 T278 R D A L L T L T A S A P F D V
Zebra Danio Brachydanio rerio Q1LV17 605 64887 S244 R D A L H T L S G C T P F N V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784488 661 71839 S267 R Q T L A T L S T C T P F E V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20.4 44.4 98.8 N.A. 96.4 45.2 N.A. 27.7 N.A. 46.9 52.5 N.A. N.A. N.A. N.A. 37.9
Protein Similarity: 100 31.8 54 99.3 N.A. 97.2 54.7 N.A. 32.5 N.A. 58.7 65.7 N.A. N.A. N.A. N.A. 51.5
P-Site Identity: 100 6.6 46.6 100 N.A. 100 46.6 N.A. 0 N.A. 60 60 N.A. N.A. N.A. N.A. 53.3
P-Site Similarity: 100 33.3 66.6 100 N.A. 100 66.6 N.A. 0 N.A. 80 66.6 N.A. N.A. N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 0 10 30 0 20 50 0 40 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 70 0 0 0 0 0 % C
% Asp: 0 40 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 30 0 0 0 0 10 0 0 0 0 10 10 30 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 60 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 30 0 0 0 0 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 10 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 80 60 0 80 0 0 0 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 0 40 0 % N
% Pro: 0 10 0 0 0 0 0 0 0 0 0 80 0 0 0 % P
% Gln: 0 10 30 0 10 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 50 0 10 10 0 0 0 0 % S
% Thr: 10 0 30 0 0 50 0 10 10 0 40 0 0 0 0 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 80 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _