Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IRF2BP1 All Species: 9.09
Human Site: S478 Identified Species: 22.22
UniProt: Q8IU81 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IU81 NP_056464.1 584 61688 S478 R N G E A E V S P T A G A E A
Chimpanzee Pan troglodytes Q5YCW1 776 80960 G596 K N V K S K I G S T E N L K H
Rhesus Macaque Macaca mulatta Q2MJS2 794 82427 A688 V A P P P P S A H P G M D Q V
Dog Lupus familis XP_541548 584 61625 S478 R N G E A E V S P T A G A E A
Cat Felis silvestris
Mouse Mus musculus Q8R3Y8 584 61732 S478 R N G E A E V S P T A G A E A
Rat Rattus norvegicus Q5EIC4 783 81477 A677 V A P P P P S A H P G M D Q V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519945 226 23147 G127 A G G P E P A G H P A G L P D
Chicken Gallus gallus
Frog Xenopus laevis Q6PCG7 690 72830 P584 V A P A G G A P H L G M D Q V
Zebra Danio Brachydanio rerio Q1LV17 605 64887 P499 A G S S T G G P A T V T D Q S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784488 661 71839 G555 S Q A T I P H G Q E A S V T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20.4 44.4 98.8 N.A. 96.4 45.2 N.A. 27.7 N.A. 46.9 52.5 N.A. N.A. N.A. N.A. 37.9
Protein Similarity: 100 31.8 54 99.3 N.A. 97.2 54.7 N.A. 32.5 N.A. 58.7 65.7 N.A. N.A. N.A. N.A. 51.5
P-Site Identity: 100 13.3 0 100 N.A. 100 0 N.A. 20 N.A. 0 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 53.3 13.3 100 N.A. 100 13.3 N.A. 20 N.A. 6.6 20 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 30 10 10 30 0 20 20 10 0 50 0 30 0 30 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 40 0 10 % D
% Glu: 0 0 0 30 10 30 0 0 0 10 10 0 0 30 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 20 40 0 10 20 10 30 0 0 30 40 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 40 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 10 0 10 0 0 0 0 0 0 0 10 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 10 0 0 20 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 30 0 0 0 % M
% Asn: 0 40 0 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 30 30 20 40 0 20 30 30 0 0 0 10 0 % P
% Gln: 0 10 0 0 0 0 0 0 10 0 0 0 0 40 0 % Q
% Arg: 30 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 10 10 10 0 20 30 10 0 0 10 0 0 20 % S
% Thr: 0 0 0 10 10 0 0 0 0 50 0 10 0 10 0 % T
% Val: 30 0 10 0 0 0 30 0 0 0 10 0 10 0 30 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _