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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRF2BP1
All Species:
9.09
Human Site:
S491
Identified Species:
22.22
UniProt:
Q8IU81
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IU81
NP_056464.1
584
61688
S491
E
A
V
S
G
G
G
S
G
T
G
A
T
P
G
Chimpanzee
Pan troglodytes
Q5YCW1
776
80960
K609
K
H
Q
P
G
G
G
K
V
Q
I
I
N
K
K
Rhesus Macaque
Macaca mulatta
Q2MJS2
794
82427
P701
Q
V
H
P
Q
N
I
P
D
S
P
M
A
N
S
Dog
Lupus familis
XP_541548
584
61625
S491
E
A
V
S
G
G
G
S
G
T
G
A
T
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3Y8
584
61732
S491
E
A
V
S
G
G
G
S
G
T
G
A
T
P
G
Rat
Rattus norvegicus
Q5EIC4
783
81477
P690
Q
V
H
P
Q
N
I
P
D
S
P
M
A
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519945
226
23147
G140
P
D
S
S
L
A
A
G
V
P
L
C
C
T
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PCG7
690
72830
P597
Q
V
H
P
Q
N
I
P
D
S
P
M
A
N
S
Zebra Danio
Brachydanio rerio
Q1LV17
605
64887
E512
Q
S
A
V
M
G
G
E
G
S
A
G
G
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784488
661
71839
P568
T
S
N
T
S
N
L
P
D
S
S
M
H
M
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.4
44.4
98.8
N.A.
96.4
45.2
N.A.
27.7
N.A.
46.9
52.5
N.A.
N.A.
N.A.
N.A.
37.9
Protein Similarity:
100
31.8
54
99.3
N.A.
97.2
54.7
N.A.
32.5
N.A.
58.7
65.7
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
20
0
100
N.A.
100
0
N.A.
6.6
N.A.
0
26.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
26.6
13.3
100
N.A.
100
13.3
N.A.
6.6
N.A.
13.3
46.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
30
10
0
0
10
10
0
0
0
10
30
30
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
40
0
0
0
0
0
0
% D
% Glu:
30
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
40
50
50
10
40
0
30
10
10
10
40
% G
% His:
0
10
30
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
30
0
0
0
10
10
0
0
10
% I
% Lys:
10
0
0
0
0
0
0
10
0
0
0
0
0
10
10
% K
% Leu:
0
0
0
0
10
0
10
0
0
0
10
0
0
0
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
40
0
10
0
% M
% Asn:
0
0
10
0
0
40
0
0
0
0
0
0
10
30
0
% N
% Pro:
10
0
0
40
0
0
0
40
0
10
30
0
0
30
0
% P
% Gln:
40
0
10
0
30
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
20
10
40
10
0
0
30
0
50
10
0
0
0
30
% S
% Thr:
10
0
0
10
0
0
0
0
0
30
0
0
30
10
0
% T
% Val:
0
30
30
10
0
0
0
0
20
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _