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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRF2BP1
All Species:
31.52
Human Site:
Y318
Identified Species:
77.04
UniProt:
Q8IU81
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IU81
NP_056464.1
584
61688
Y318
S
G
F
K
Y
L
E
Y
E
R
R
H
G
S
G
Chimpanzee
Pan troglodytes
Q5YCW1
776
80960
D389
S
K
D
G
T
G
S
D
D
K
K
A
K
T
S
Rhesus Macaque
Macaca mulatta
Q2MJS2
794
82427
Y460
S
G
F
K
Y
L
E
Y
E
K
K
H
G
S
G
Dog
Lupus familis
XP_541548
584
61625
Y318
S
G
F
K
Y
L
E
Y
E
R
R
H
G
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3Y8
584
61732
Y318
S
G
F
K
Y
L
E
Y
E
R
R
H
G
S
G
Rat
Rattus norvegicus
Q5EIC4
783
81477
Y449
S
G
F
K
Y
L
E
Y
E
K
K
H
G
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519945
226
23147
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PCG7
690
72830
Y358
S
G
F
K
Y
L
E
Y
E
K
K
H
G
S
G
Zebra Danio
Brachydanio rerio
Q1LV17
605
64887
Y321
S
G
Y
K
Y
V
E
Y
E
K
R
H
G
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784488
661
71839
Y346
S
G
Y
K
Y
L
E
Y
E
K
K
H
G
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.4
44.4
98.8
N.A.
96.4
45.2
N.A.
27.7
N.A.
46.9
52.5
N.A.
N.A.
N.A.
N.A.
37.9
Protein Similarity:
100
31.8
54
99.3
N.A.
97.2
54.7
N.A.
32.5
N.A.
58.7
65.7
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
6.6
86.6
100
N.A.
100
86.6
N.A.
0
N.A.
86.6
73.3
N.A.
N.A.
N.A.
N.A.
73.3
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
0
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
80
0
80
0
0
0
0
0
0
% E
% Phe:
0
0
60
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
80
0
10
0
10
0
0
0
0
0
0
80
0
70
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
80
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
80
0
0
0
0
0
60
50
0
10
0
0
% K
% Leu:
0
0
0
0
0
70
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
30
40
0
0
0
0
% R
% Ser:
90
0
0
0
0
0
10
0
0
0
0
0
0
70
10
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
0
0
20
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
20
0
80
0
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _