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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LASS3 All Species: 29.39
Human Site: T109 Identified Species: 64.67
UniProt: Q8IU89 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IU89 NP_849164.2 383 46217 T109 L A K K C N L T E R Q V E R W
Chimpanzee Pan troglodytes XP_001141298 383 46214 T109 L A K K C N L T E R Q V E R W
Rhesus Macaque Macaca mulatta XP_001082667 385 46517 T109 L A K K C N L T E R Q V E R W
Dog Lupus familis XP_849881 457 54949 T175 L A K K C N L T E R Q V E R W
Cat Felis silvestris
Mouse Mus musculus Q924Z4 380 45006 S110 L S R Q S G L S G R Q V E R W
Rat Rattus norvegicus NP_001121033 391 47216 T109 L A K K C N L T E R Q V E R W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519596 334 40121 N91 L E N F F I R N S R K P S Q T
Chicken Gallus gallus XP_424275 286 34432 Y43 F P K P Q Q L Y A T I P Y A F
Frog Xenopus laevis NP_001085735 372 43975 T110 L A K K S N R T S I Q V E R W
Zebra Danio Brachydanio rerio XP_694530 380 45048 S112 L C K K C G W S S R Q V E R W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q6NQI8 308 36530 D64 H R Q D M G D D T T E R K K K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 95.5 74.8 N.A. 51.4 76.4 N.A. 71.2 46.7 50.6 52.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 98.1 79.4 N.A. 67.6 86.6 N.A. 78 55 69.4 70.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 53.3 100 N.A. 13.3 13.3 73.3 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 80 100 N.A. 26.6 20 73.3 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 55 0 0 0 0 0 0 10 0 0 0 0 10 0 % A
% Cys: 0 10 0 0 55 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 10 10 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 46 0 10 0 73 0 0 % E
% Phe: 10 0 0 10 10 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 0 0 28 0 0 10 0 0 0 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 10 10 0 0 0 0 % I
% Lys: 0 0 73 64 0 0 0 0 0 0 10 0 10 10 10 % K
% Leu: 82 0 0 0 0 0 64 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 55 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 10 0 0 0 0 0 0 0 19 0 0 0 % P
% Gln: 0 0 10 10 10 10 0 0 0 0 73 0 0 10 0 % Q
% Arg: 0 10 10 0 0 0 19 0 0 73 0 10 0 73 0 % R
% Ser: 0 10 0 0 19 0 0 19 28 0 0 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 55 10 19 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 73 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 73 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _